In the relentless pursuit of more effective cancer treatments, pharmaceutical researchers constantly seek compounds that can optimize the performance of existing therapies. Gimeracil, with its CAS number 103766-25-2, has emerged as a crucial player in this arena, acting as a potent inhibitor of dihydropyrimidine dehydrogenase (DPD). As a specialized manufacturer and supplier of fine chemicals in China, we provide high-quality Gimeracil to empower advancements in oncology.

The therapeutic significance of Gimeracil is deeply rooted in its biochemical function. DPD is the rate-limiting enzyme responsible for the catabolism of pyrimidine analogs, a class of drugs that includes vital chemotherapeutic agents like 5-fluorouracil (5-FU). By inhibiting DPD activity, Gimeracil effectively slows down the degradation of 5-FU, leading to higher and more sustained drug concentrations within the patient's system. This enhanced exposure time allows the chemotherapy to exert a more profound cytotoxic effect on rapidly dividing cancer cells, thereby improving treatment efficacy and potentially overcoming resistance mechanisms.

Moreover, Gimeracil contributes to cancer treatment by acting as a radiosensitizer. This means it can increase the sensitivity of tumor cells to radiation therapy. The proposed mechanism involves interfering with DNA repair pathways, specifically homologous recombination, which cancer cells often employ to repair radiation-induced DNA damage. By disrupting this repair process, Gimeracil makes cancer cells more vulnerable to the damaging effects of radiation, creating a synergistic effect when used in combination.

For pharmaceutical companies and research institutions worldwide, securing a reliable source of Gimeracil is essential. We pride ourselves on being a premier Chinese manufacturer and supplier, dedicated to delivering Gimeracil of exceptional purity, typically 99% or higher. Our production facilities are equipped with advanced technology, and we rigorously adhere to quality control protocols. This ensures that the Gimeracil you buy from us is consistent, reliable, and suitable for demanding pharmaceutical applications, from preclinical research to clinical trial support.

Choosing to purchase Gimeracil from our manufacturing base in China offers significant benefits. We provide competitive pricing, making it feasible for researchers to acquire larger quantities for extensive studies. Our commitment extends beyond just supplying the chemical; we aim to be a strategic partner. This includes offering comprehensive product documentation, flexible packaging options (such as 25kg drums), and responsive customer support to address all your Gimeracil-related inquiries. We understand the importance of a stable supply chain for your ongoing projects.

We encourage prospective buyers to engage with us directly to learn more about our Gimeracil product. Whether you are a procurement manager looking for bulk supply or a research scientist needing specific technical details, our team is ready to assist. We are committed to facilitating your research and development efforts by providing this critical pharmaceutical intermediate with unparalleled quality and service. Explore the potential of Gimeracil and partner with a trusted Chinese manufacturer for your supply needs.

In essence, Gimeracil (CAS 103766-25-2) is a cornerstone compound for enhancing cancer therapy outcomes. Its unique properties as a DPD inhibitor and radiosensitizer make it invaluable in modern oncology. We are dedicated to supplying this vital chemical intermediate with the highest standards of quality and reliability, supporting the global fight against cancer. Contact us to buy Gimeracil and elevate your research and therapeutic development.