In the complex landscape of cancer treatment, targeted therapies and optimized drug delivery are paramount. One compound that plays a significant role in enhancing the efficacy of certain chemotherapeutic agents is Gimeracil, identified by CAS number 103766-25-2. As a leading pharmaceutical intermediate manufacturer in China, we are committed to providing high-quality Gimeracil to support cutting-edge research and clinical applications.

Gimeracil is primarily known as a potent inhibitor of dihydropyrimidine dehydrogenase (DPD). DPD is an enzyme that plays a critical role in the catabolism, or breakdown, of pyrimidine-based drugs. Many widely used chemotherapy drugs, such as 5-fluorouracil (5-FU) and its derivatives like Tegafur, fall into this category. By inhibiting DPD, Gimeracil effectively prolongs the circulating concentrations of these vital antitumor agents in the body. This extended presence means the drugs can remain active for longer periods, leading to more effective cancer cell destruction and potentially improved patient outcomes.

Beyond its role in drug metabolism, Gimeracil has also demonstrated potential as a radiosensitizer. This means it can make cancer cells more susceptible to radiation therapy. Its mechanism in this regard is believed to involve the inhibition of homologous recombination, a key process that cancer cells utilize to repair DNA damage, including that caused by radiation. By interfering with this repair mechanism, Gimeracil can enhance the cell-killing effects of radiotherapy.

For pharmaceutical researchers, drug developers, and procurement managers, sourcing reliable and high-purity Gimeracil is crucial. We understand these needs and are proud to be a trusted manufacturer and supplier of Gimeracil from China. Our commitment to quality ensures that every batch meets rigorous standards, typically exceeding 99% purity, with certifications such as GMP and SGS available. This dedication guarantees that researchers can confidently incorporate our Gimeracil into their studies and formulations.

When considering where to buy Gimeracil, choosing a reputable supplier like us offers distinct advantages. We provide competitive pricing for bulk orders, essential for cost-effective research and development. Our aim is to facilitate access to this critical compound, supporting advancements in oncology. Whether you are developing new therapeutic combinations or investigating novel cancer treatment strategies, our Gimeracil is a reliable choice.

We offer various packaging options, commonly in 25kg drums, ensuring safe and stable storage. For those looking to purchase Gimeracil, we encourage you to reach out to us for detailed product specifications, pricing, and sample requests. Our team is dedicated to providing excellent customer service, assisting you with your inquiries and ensuring a smooth procurement process. Invest in quality and reliability for your cancer research – buy Gimeracil from our China-based manufacturing facility.

In summary, Gimeracil (CAS 103766-25-2) is an indispensable pharmaceutical intermediate for modern cancer therapy. Its ability to inhibit DPD and act as a radiosensitizer makes it a valuable asset in the fight against cancer. As a leading manufacturer and supplier, we are poised to meet your demand for this critical compound, offering purity, reliability, and value. Contact us today to discuss your requirements and secure your supply of Gimeracil.