In the critical field of pharmaceutical research and development, the availability of reliable, high-purity chemical intermediates is paramount. Gimeracil, known by its CAS number 103766-25-2, is one such vital compound, primarily recognized for its role as a potent inhibitor of dihydropyrimidine dehydrogenase (DPD). As a leading manufacturer and supplier of specialized chemicals based in China, we are committed to providing Gimeracil that meets the stringent demands of the global pharmaceutical industry.

Gimeracil's therapeutic significance lies in its ability to modulate the metabolism of pyrimidine-based chemotherapy drugs. DPD is the rate-limiting enzyme in the catabolism of these essential anticancer agents, such as 5-fluorouracil (5-FU). By inhibiting DPD, Gimeracil effectively prolongs the in-vivo half-life of 5-FU, allowing it to remain active in the body for longer periods. This extended exposure can lead to enhanced cytotoxicity against cancer cells and, consequently, improved treatment efficacy. Researchers and clinicians value Gimeracil for its contribution to optimizing chemotherapy regimens.

Beyond its direct impact on drug metabolism, Gimeracil also functions as a radiosensitizer. This means it can increase the sensitivity of cancer cells to radiation therapy. The proposed mechanism involves hindering the cellular processes that cancer cells use to repair radiation-induced DNA damage, particularly through the inhibition of homologous recombination. This synergistic action between Gimeracil and radiation therapy can lead to more effective tumor eradication.

For procurement managers and research scientists, securing a dependable supply of high-purity Gimeracil is a key consideration. We, as a reputable Chinese manufacturer, offer Gimeracil with a guaranteed minimum purity of 99%. Our state-of-the-art manufacturing facilities and rigorous quality control protocols ensure product consistency and reliability. When you choose to buy Gimeracil from us, you are investing in quality backed by extensive industry experience.

Sourcing Gimeracil from China through our company provides significant advantages, including competitive pricing, especially for bulk orders. We understand the importance of a stable supply chain for pharmaceutical research and production. Therefore, we maintain efficient manufacturing processes and robust logistics to ensure timely deliveries to our international clients. Our commitment to customer satisfaction extends to providing comprehensive product data, including Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS), to facilitate your procurement and research processes.

We encourage all potential customers to reach out to us for their Gimeracil (CAS 103766-25-2) needs. Whether you are conducting preclinical research, involved in drug formulation, or require material for clinical trials, our team is ready to provide expert assistance and ensure your requirements are met. We are dedicated to supporting the advancement of cancer therapies by supplying this critical pharmaceutical intermediate with unparalleled quality and service.

In conclusion, Gimeracil (CAS 103766-25-2) is an essential compound in modern oncology, enhancing the effectiveness of both chemotherapy and radiation therapy. As a leading Chinese manufacturer and supplier, we are committed to providing high-purity Gimeracil to support global research and therapeutic development. Contact us today to buy Gimeracil and partner with a reliable source to advance your important work in cancer treatment.