The pharmaceutical industry is constantly seeking novel compounds and efficient synthesis pathways to develop life-saving drugs. At the heart of this innovation are specialized chemical intermediates, such as 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone (CAS 1378387-81-5). This complex fluorene derivative plays a vital role as a building block in the creation of advanced pharmaceutical agents. For researchers and procurement specialists, understanding its properties and how to source it reliably is key.

The Chemical Profile of 1378387-81-5

This specific fluorene intermediate, bearing CAS number 1378387-81-5, is distinguished by its intricate structure: a 7-bromo, 9,9-difluorinated fluorene core attached to a 2-chloroethanone moiety. Typically presented as a white to light yellow powder or crystalline solid, its high purity, often above 99.0%, is a critical attribute for its intended pharmaceutical applications. This purity ensures predictable reaction outcomes and minimizes unwanted by-products in downstream synthesis steps, a crucial consideration for any buyer prioritizing product quality and regulatory compliance.

Why Fluorene Intermediates Matter in Pharma

Fluorene derivatives, due to their rigid, planar structures and the ease with which they can be functionalized, are increasingly important in medicinal chemistry. They serve as scaffolds for designing molecules with specific biological activities. 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone is a prime example, serving as a critical precursor in the synthesis of remipavir and other therapeutic compounds. Its strategic incorporation into synthetic routes allows for the precise construction of complex molecular architectures required for efficacy and safety in pharmaceuticals. When considering purchasing this material, looking for a manufacturer that specializes in such complex organic synthesis is advisable.

Ensuring a Reliable Supply: Partnering with Manufacturers

The global demand for high-purity pharmaceutical intermediates necessitates a robust and reliable supply chain. For chemists and procurement managers, identifying a trustworthy manufacturer is paramount. Direct sourcing from manufacturers based in China, such as NINGBO INNO PHARMCHEM CO.,LTD., often provides access to competitive pricing, stringent quality control, and direct technical communication. We are dedicated to providing consistent availability and quality for 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone, supporting your research and development efforts. We aim to be your go-to supplier for this essential chemical intermediate.

Making Informed Purchase Decisions

When you need to purchase CAS 1378387-81-5, prioritize manufacturers that offer:

  • Comprehensive Quality Documentation: Availability of detailed CoAs is essential.
  • Production Capacity: Ensure the manufacturer can meet your volume requirements, from R&D scales to bulk orders.
  • Expertise in Fluorine Chemistry: Specialized knowledge is beneficial for complex intermediates.
  • Transparent Pricing and Lead Times: Clear communication on cost and delivery schedules is vital for project planning.

NINGBO INNO PHARMCHEM CO.,LTD. stands ready to meet your needs for high-quality 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone. We encourage you to reach out to us for inquiries regarding pricing, samples, and to discuss how we can support your pharmaceutical synthesis projects.