In the dynamic world of pharmaceutical manufacturing and organic synthesis, the availability of high-quality, specialized intermediates is paramount. For researchers and procurement managers alike, understanding the properties and sourcing channels for these crucial building blocks is key to project success. This guide focuses on 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone, identified by CAS number 1378387-81-5, a compound gaining attention for its role in advanced pharmaceutical applications.

Understanding the Intermediate: CAS 1378387-81-5

The compound, chemically known as 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone, is a complex organic molecule characterized by its unique fluorene backbone substituted with bromine and fluorine atoms, along with a chloroacetyl group. These structural features make it a valuable intermediate for chemists involved in creating novel therapeutic agents. Its appearance is typically described as a white to light yellow powder or crystal, with a high purity level, often exceeding 99.0%, which is non-negotiable for stringent pharmaceutical manufacturing standards.

Key Applications and Importance in Synthesis

The primary significance of 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone lies in its utility as an intermediate for the synthesis of remipavir and other significant active pharmaceutical ingredients (APIs). Its specific chemical structure allows for targeted reactions, enabling the efficient construction of complex drug molecules. For procurement managers looking to secure a reliable supply chain for such intermediates, understanding these applications is crucial for making informed purchasing decisions. Identifying a reputable manufacturer that can consistently deliver this material is essential for ongoing production.

Navigating the Sourcing Landscape: Manufacturer vs. Supplier

When seeking to purchase CAS 1378387-81-5, it's important to distinguish between a manufacturer and a supplier. Manufacturers, like ourselves at NINGBO INNO PHARMCHEM CO.,LTD., have direct control over the production process, ensuring quality from raw material to finished product. This control is vital for consistent purity and adherence to specifications. Suppliers may source from multiple manufacturers, which can sometimes lead to variations in quality or availability. For critical intermediates like this fluorene derivative, partnering directly with a reliable manufacturer in China can offer significant advantages in terms of price, quality assurance, and technical support. We are committed to being your trusted source.

Factors to Consider When Buying

Several factors should influence your decision when buying 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone:

  • Purity Levels: Always verify the stated purity (e.g., ≥99.0%) and ask for Certificates of Analysis (CoA).
  • CAS Number Verification: Ensure the CAS number 1378387-81-5 is correctly listed and matches your requirements.
  • Manufacturer Reputation: Research the background and certifications of potential manufacturers.
  • Lead Times and MOQ: Understand the minimum order quantity (MOQ) and typical lead times for production and delivery.
  • Technical Support: A good manufacturer will offer technical assistance and custom synthesis services if needed.

For those in need of this specialized pharmaceutical intermediate, engaging with experienced chemical manufacturers is the most effective strategy. We pride ourselves on our ability to supply high-quality 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone, supporting innovation in the pharmaceutical sector. If you are looking to buy this compound or require custom synthesis services, do not hesitate to contact us for a quote and sample.