The relentless pursuit of new and effective pharmaceutical treatments necessitates a deep understanding and strategic sourcing of advanced chemical intermediates. Among these, 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone, bearing the CAS number 1378387-81-5, emerges as a compound of significant interest for its role in complex organic synthesis, particularly within the pharmaceutical sector. For professionals involved in R&D and manufacturing, knowing how to effectively procure this specialized intermediate is crucial.

Understanding the Intermediate: 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone

This fluorene derivative is a sophisticated building block characterized by its unique molecular structure, which includes bromine and difluoro substitutions on the fluorene core, along with a chloroacetyl group. Typically presented as a white to light yellow powder or crystal, its high purity, frequently specified as ≥99.0%, is a defining characteristic. This level of purity is critical for ensuring the precision and reliability required in multi-step pharmaceutical synthesis, such as in the production of remipavir. Pharmaceutical scientists and procurement specialists value such intermediates for their ability to streamline complex reaction pathways and contribute to the development of safe and effective medicines.

The Strategic Importance of Fluorene Derivatives in Pharma

Fluorene-based compounds have garnered considerable attention in medicinal chemistry due to their rigid, planar structure and versatility in functionalization. They serve as excellent scaffolds for designing molecules with targeted biological activities. 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone exemplifies this, offering a pre-functionalized core that can be readily transformed into more complex drug candidates. For buyers looking to purchase this intermediate, partnering with a manufacturer that possesses expertise in complex organic synthesis and fluorination chemistry is highly recommended.

Partnering with Manufacturers for Quality and Value

To ensure the highest quality and most reliable supply of CAS 1378387-81-5, engaging directly with manufacturers is the most effective approach. NINGBO INNO PHARMCHEM CO.,LTD., as a leading chemical supplier in China, specializes in producing high-purity pharmaceutical intermediates. Our commitment to stringent quality control and efficient manufacturing processes means we can offer consistent product quality and competitive pricing. We understand the critical role this intermediate plays in pharmaceutical innovation and are dedicated to supporting your projects by being a dependable supplier.

Key Considerations for Buyers

  • Purity Assurance: Always verify the ≥99.0% purity claim with a Certificate of Analysis.
  • Manufacturer Capabilities: Assess their experience with fluorene chemistry and similar complex intermediates.
  • Supply Chain Management: Ensure the manufacturer can guarantee timely delivery and adequate stock for your needs.
  • Technical Collaboration: A responsive manufacturer can provide valuable technical support and discuss custom synthesis options.

NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner for 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone. We invite all interested parties to reach out to us for inquiries, quotes, and samples, and to discover how our high-quality products can advance your pharmaceutical development goals.