The global demand for effective cardiovascular treatments, such as Rosuvastatin Calcium, continues to grow, underscoring the importance of reliable access to high-quality pharmaceutical intermediates. One such critical component is [[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]methyl]triphenylphosphonium Bromide, identified by its CAS number 154057-58-6. This advanced chemical intermediate is essential for the synthesis of this widely used statin drug. For procurement professionals and R&D scientists, understanding its properties and how to source it efficiently is key.

Product Specifications and Importance

[[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]methyl]triphenylphosphonium Bromide is a specialized organophosphorus compound. It typically presents as a white to off-white powder, with a guaranteed high purity, often specified at ≥98.0%. This level of purity is crucial because it directly impacts the efficiency and outcome of downstream chemical reactions, particularly in the complex synthesis of Active Pharmaceutical Ingredients (APIs) like Rosuvastatin Calcium. Low loss on drying (≤1.0%) further indicates the careful handling and manufacturing processes employed by reputable suppliers.

The primary application for this phosphonium salt is its role as a precursor in the Wittig reaction or related olefination chemistries. These reactions are indispensable for constructing the specific carbon-carbon double bonds required in the molecular structure of Rosuvastatin Calcium, contributing significantly to its pharmacological activity. Therefore, sourcing this intermediate from a trusted manufacturer ensures that your production process begins with a foundation of consistent quality and reliability.

Finding Reliable Suppliers and Competitive Pricing

When seeking to purchase [[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]methyl]triphenylphosphonium Bromide, it is vital to identify suppliers who can meet stringent pharmaceutical standards. Look for manufacturers with a proven track record in producing high-purity fine chemicals and pharmaceutical intermediates. Key aspects to consider include:

  • Quality Certifications: Reputable suppliers often hold ISO certifications and demonstrate robust internal quality control systems.
  • Technical Data: Availability of detailed specifications, Certificates of Analysis (CoA), and Material Safety Data Sheets (MSDS) is essential.
  • Supply Chain Stability: Ensuring a consistent and uninterrupted supply is critical for production continuity.
  • Competitive Pricing: Requesting quotes for bulk purchases will help secure cost-effective solutions without compromising quality.

As a dedicated manufacturer and supplier of pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. offers [[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]methyl]triphenylphosphonium Bromide for sale. We are committed to providing high-purity chemicals sourced from China to meet the demands of the global pharmaceutical industry. If you are looking to buy this essential intermediate, contact us to discuss your requirements, obtain a quote, and ensure a reliable supply for your manufacturing operations.