For professionals in the pharmaceutical and fine chemical sectors, staying abreast of market dynamics for key intermediates is crucial. 1,2,3-Triacetyl-5-deoxy-D-ribose (CAS 62211-93-2) stands out as a significant compound, primarily recognized for its role in the synthesis of Capecitabine. This article delves into the market landscape, offering guidance on sourcing this vital intermediate and highlighting its importance.

The Market for 1,2,3-Triacetyl-5-deoxy-D-ribose

The demand for 1,2,3-Triacetyl-5-deoxy-D-ribose is closely tied to the global pharmaceutical market, particularly the segment focused on oncology drugs. As cancer treatments evolve and demand for effective therapies like Capecitabine grows, so does the need for reliable suppliers of its key building blocks. The market is characterized by a network of manufacturers, distributors, and custom synthesis providers, offering the compound in various grades and quantities.

Key Considerations for Procurement Professionals

When engaging in the purchase of 1,2,3-Triacetyl-5-deoxy-D-ribose, procurement managers must prioritize several factors:

  • Supplier Location and Reliability: Identifying established manufacturers of CAS 62211-93-2, especially those with a strong presence in regions known for chemical production like China, can offer advantages in terms of cost and volume. It's essential to vet suppliers for their production capacity, quality control systems, and delivery track record.
  • Quality Specifications: As mentioned, purity is key. Ensure the product meets the required specifications (e.g., ≥98% purity) and that the supplier provides a comprehensive Certificate of Analysis (CoA).
  • Pricing and Volume: Obtaining competitive pricing for 1,2,3-Triacetyl-5-deoxy-D-ribose is vital for cost management. Bulk purchase inquiries should be directed to manufacturers who can offer tiered pricing based on volume.
  • Regulatory Compliance: For pharmaceutical use, understanding the regulatory compliance of the supplier and the product itself is important, even at the intermediate stage.

Spotlight on Applications: Capecitabine Synthesis

The primary driver for the demand for 1,2,3-Triacetyl-5-deoxy-D-ribose is its role as a critical intermediate in the synthesis of Capecitabine. This compound provides the necessary chiral framework and functional groups that are transformed through subsequent chemical reactions to yield the final drug. Researchers and manufacturers looking to buy Capecitabine intermediates will inevitably encounter this crucial compound.

Sourcing Strategies and Best Practices

To effectively navigate the market, consider these strategies:

  • Utilize Online Chemical Marketplaces: Platforms that connect buyers with verified manufacturers and suppliers can be a valuable starting point for identifying potential partners.
  • Direct Manufacturer Engagement: Reaching out directly to known manufacturers can sometimes yield better pricing and more detailed technical information.
  • Comparative Quotations: Always request multiple quotes to compare pricing, lead times, and terms of service.

In conclusion, 1,2,3-Triacetyl-5-deoxy-D-ribose is a high-value intermediate with significant implications for the pharmaceutical industry. By understanding market dynamics and employing a strategic sourcing approach, companies can secure a reliable supply of this essential chemical building block, supporting the development and production of critical cancer therapies.