In the pursuit of scientific understanding and the development of new therapies, the precision of research tools is of utmost importance. Ion channels, integral to cellular communication and function, present a complex area of study. The TASK-1 (KCNK3) potassium channel, a key player in regulating neuronal excitability and sensory signaling, is a prime example. For researchers aiming to isolate and understand the specific contributions of TASK-1, selective inhibitors are indispensable. ML365 stands out as a premier compound in this regard.

ML365, identified by its CAS number 947914-18-3, is a highly effective small molecule inhibitor that targets the TASK-1 potassium channel with remarkable potency and selectivity. Boasting an IC50 value of 4 nM for TASK-1, it demonstrates significantly higher efficacy against this channel compared to other K2P family members like TASK-3, and even more so against unrelated potassium channels. This specificity minimizes off-target effects, ensuring that observed biological responses can be reliably attributed to the modulation of TASK-1. This makes ML365 an invaluable asset for precise in vitro experiments and early-stage drug discovery.

For scientific laboratories and research institutions, the consistent supply of high-purity, well-characterized compounds is critical for the reproducibility of experiments. As a leading manufacturer and supplier, we are dedicated to providing ML365 that meets exacting purity standards (≥98% by HPLC). This ensures that our clients receive a reliable reagent, empowering them to achieve accurate and meaningful research outcomes. When you decide to buy ML365 from us, you are choosing a partner committed to research integrity.

The benefits of using selective inhibitors like ML365 extend to optimizing research workflows and accelerating discovery. By providing a clear and targeted approach to TASK-1 modulation, researchers can gain deeper insights into its roles in pain perception, respiratory control, and other physiological processes. This leads to a more efficient progression of research projects, from basic science to potential therapeutic applications.

We offer ML365 at competitive prices, understanding the budgetary constraints faced by many research organizations. Our streamlined purchasing process and efficient global shipping ensure that you can acquire this vital research chemical promptly. If you are looking to purchase ML365 or require custom synthesis services, our team of experts is ready to assist you. We welcome inquiries for quotes and samples.

Elevate your research with the precision and quality of ML365. Partner with a trusted supplier committed to providing the tools that drive scientific innovation and contribute to a better understanding of crucial biological pathways.