For chemical manufacturers and procurement specialists, the strategic selection of chemical intermediates is fundamental to optimizing synthesis processes, controlling costs, and ensuring the quality of the final product. 2-Phenoxyethyl Chloride (CAS: 622-86-6) is one such intermediate that holds significant importance across various sectors, particularly in pharmaceuticals and fine chemical production.

The Chemical Foundation: Properties of 2-Phenoxyethyl Chloride

With the molecular formula C8H9ClO and a molecular weight of 156.61 g/mol, 2-Phenoxyethyl Chloride is a compound that combines an aromatic phenoxy group with a reactive chloroethyl functionality. Typically presented as a white to off-white solid, it possesses a melting point of 28°C and a boiling point of around 219°C. These physical characteristics, alongside a density of approximately 1.13 g/mL, contribute to its manageable handling and predictable behavior in chemical reactions. Its chemical structure makes it an excellent substrate for nucleophilic substitution and various coupling reactions.

Strategic Role in Chemical Synthesis

The primary value of 2-Phenoxyethyl Chloride lies in its role as a versatile building block. In pharmaceutical synthesis, it is a key intermediate for producing important APIs, such as those used in antidepressants and cancer therapies. For researchers and manufacturers looking to buy 2-Phenoxyethyl Chloride, its proven efficacy in these established pathways is a major draw. Beyond pharmaceuticals, it serves as a precursor in the synthesis of fine chemicals and materials, demonstrating broad applicability in chemical R&D and industrial production.

The compound’s ability to introduce the phenoxyethyl group into complex molecular architectures makes it invaluable for creating specific chemical properties. This versatility means that a reliable supply of high-purity 2-Phenoxyethyl Chloride is essential for maintaining consistent production schedules and ensuring the quality of manufactured goods.

Procurement Best Practices

To effectively purchase 2-Phenoxyethyl Chloride, chemical companies should focus on several key areas:

  • Quality Assurance: Always prioritize suppliers that guarantee high purity levels (often ≥98.0%) and minimal impurities, especially for pharmaceutical applications. A detailed Certificate of Analysis (CoA) is essential.
  • Supplier Reliability: Selecting a trusted 2-Phenoxyethyl Chloride supplier with a proven history of consistent production and on-time delivery is critical for maintaining operational continuity.
  • Cost-Effectiveness: Investigating the 2-Phenoxyethyl Chloride price from different sources, particularly from a reputable manufacturer in China, can lead to significant cost savings, especially when purchasing in bulk.
  • Technical Support: Engaging with suppliers who offer robust technical support can assist in overcoming synthesis challenges and optimizing process parameters.

By strategically sourcing 2-Phenoxyethyl Chloride, manufacturers can enhance the efficiency and cost-effectiveness of their synthesis operations, ensuring they remain competitive in the global chemical market. Accessing this vital intermediate from reliable manufacturers is a cornerstone of successful chemical production.