For professionals in the chemical industry, a deep understanding of the properties of key intermediates like 2-Phenoxyethyl Chloride (CAS: 622-86-6) is crucial for optimizing processes and ensuring product quality. This compound plays a significant role in various industrial applications, making its sourcing and handling a focal point for many chemical manufacturers and researchers.

Physicochemical Profile of 2-Phenoxyethyl Chloride

2-Phenoxyethyl Chloride, also known by synonyms such as 2-chloroethoxybenzene or beta-chlorophenetole, possesses a molecular formula of C8H9ClO and a molecular weight of 156.61 g/mol. Its physical appearance is typically described as a white or off-white solid, with a defined melting point of 28°C. The compound exhibits a boiling point of approximately 219-220°C at atmospheric pressure and a density of around 1.13 g/cm³. These properties are indicative of a relatively stable organic compound, suitable for storage and use in various industrial environments. The refractive index (n20/D) is noted at 1.534, which is a useful parameter for quality control.

Industrial Applications and Stability

The industrial significance of 2-Phenoxyethyl Chloride lies primarily in its function as a versatile intermediate in chemical synthesis. It serves as a critical building block in the pharmaceutical industry for the production of APIs like nafazodone and derivatives used in cancer therapy. Its reactive chloroethyl group allows for facile nucleophilic substitution, enabling chemists to functionalize various molecular scaffolds. This characteristic also makes it valuable in the synthesis of fine chemicals and specialty materials.

The compound is known for its good stability under typical storage conditions, provided it is kept in a tightly closed container in a cool, dry, and well-ventilated area, away from incompatible substances. This stability ensures its efficacy and reliability when used in synthetic processes, reducing concerns about degradation and ensuring consistent reaction outcomes. For any industrial operation looking to buy 2-Phenoxyethyl Chloride, understanding these stability aspects is key to effective inventory management and process integration.

Procurement and Supply Chain Considerations

When you are looking to purchase 2-Phenoxyethyl Chloride, identifying a reliable 2-Phenoxyethyl Chloride supplier is paramount. Companies often seek out manufacturers who can guarantee high purity (e.g., ≥98.0%) and low water content (≤0.1%), essential for demanding applications. Many find that sourcing from a reputable manufacturer in China offers a strategic advantage in terms of both cost-effectiveness and accessibility to large quantities. When inquiring about 2-Phenoxyethyl Chloride price, it is advisable to compare offers and check for bulk discounts.

A robust supply chain is critical for continuous industrial production. Therefore, partnering with a supplier that has a proven track record for consistent quality and timely delivery of 2-Phenoxyethyl Chloride is a significant asset. Ensuring the supplier provides essential documentation like CoAs and MSDS is also a standard practice for quality assurance in industrial procurement.

In essence, 2-Phenoxyethyl Chloride remains a vital compound in the chemical industry, contributing to advancements in pharmaceuticals and fine chemicals through its well-defined properties and versatile reactivity. Its availability from reliable sources ensures that the wheels of chemical innovation continue to turn smoothly.