For professionals in the pharmaceutical and chemical industries, the reliable procurement of high-quality intermediates is fundamental to successful product development and manufacturing. 10-Deacetylbaccatin III (CAS 32981-86-5) is one such critical intermediate, essential for the synthesis of life-saving anti-cancer drugs like paclitaxel and docetaxel. This guide focuses on how to effectively source this compound, with a particular emphasis on partnering with reputable Chinese manufacturers.

Understanding the Importance of Purity and Specifications

When considering the purchase of 10-Deacetylbaccatin III, the primary concern for any buyer should be the compound's purity and adherence to specifications. As a pharmaceutical intermediate, even minor impurities can significantly impact the efficacy and safety of the final drug product. Key specifications to scrutinize include:

  • Assay (HPLC): Look for products with assay values consistently above 98%, ideally 99% or higher, ensuring maximum yield and minimal downstream purification.
  • Appearance: Confirm that the product is consistently described as a white or almost white crystalline powder.
  • Solubility: While primarily insoluble in water, its solubility in organic solvents like DMSO or ethanol is important for laboratory use.
  • CAS Number: Always verify the CAS number as 32981-86-5 to ensure you are sourcing the correct compound.

As a leading manufacturer in China, we place immense importance on these quality parameters, ensuring that our 10-Deacetylbaccatin III meets rigorous international standards.

Navigating the Supply Chain: Choosing a Reliable Supplier

The global supply chain for pharmaceutical intermediates can be complex. When looking to buy 10-Deacetylbaccatin III, consider the following factors when selecting a supplier:

  • Manufacturing Expertise: Does the supplier have a proven track record in complex organic synthesis and natural product extraction?
  • Quality Assurance Systems: Does the manufacturer have robust quality control processes, including comprehensive analytical testing (e.g., COA, HPLC, NMR data)?
  • Supply Chain Stability: Can the supplier guarantee consistent availability and timely delivery, especially for larger orders?
  • Customer Support and Responsiveness: Is the supplier readily available to answer technical questions and provide documentation?

Partnering with an experienced 10-Deacetylbaccatin III supplier from China offers significant advantages in terms of cost-effectiveness and access to advanced manufacturing capabilities. However, due diligence in selecting a partner is crucial.

The Role of 10-Deacetylbaccatin III in Drug Synthesis

10-Deacetylbaccatin III serves as the core molecular structure upon which paclitaxel and docetaxel are built. Its availability is a bottleneck for the production of these essential chemotherapies. Therefore, securing a consistent and high-quality supply is not just a procurement task; it's a contribution to global health.

We, as a dedicated chemical manufacturer and supplier, understand the critical nature of these intermediates. We invite you to explore our offerings for 10-Deacetylbaccatin III and experience the reliability and quality that our expertise provides. Contact us to learn more about pricing and to place your order.