For procurement managers in the pharmaceutical and fine chemical industries, sourcing essential building blocks like 9-ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile (CAS 1256584-80-1) requires a strategic approach. This advanced organic compound, characterized by its unique benzocarbazole structure with specific ethyl, iodo, and nitrile substituents, is a critical intermediate in the synthesis of advanced pharmaceuticals, most notably Anaplastic Lymphoma Kinase (ALK) inhibitors.

Understanding Product Specifications

When considering a purchase, understanding the key specifications is vital. The compound is typically supplied as a white powder with a high purity level, often specified at 98%. Its molecular formula is C21H17IN2O, with a molecular weight of approximately 440.28 g/mol. The CAS number 1256584-80-1 serves as its unique identifier in chemical databases and regulatory filings. For any bulk purchase or inquiry, ensuring the supplier can provide a detailed Certificate of Analysis (CoA) confirming these specifications, along with safety data sheets (SDS), is a fundamental step in the procurement process. This diligence ensures that the material meets the stringent requirements for your specific applications, whether in research and development or large-scale manufacturing.

Identifying Reliable Suppliers and Manufacturers

The global market for fine chemicals offers a diverse range of suppliers. For a specialized intermediate like CAS 1256584-80-1, identifying a reliable manufacturer and supplier is key. Many leading chemical manufacturers are located in China, known for their robust production capabilities and competitive pricing. When evaluating a potential supplier, consider factors such as:

  • Production Capacity: Can they meet your required volume, from R&D batches to commercial-scale production?
  • Quality Control: Do they have established ISO certifications or similar quality management systems?
  • Technical Support: Do they offer technical assistance regarding product usage or synthesis?
  • Logistics and Shipping: What are their Incoterms, shipping ports (e.g., Shanghai, Qingdao), and delivery timelines?
  • Payment Terms: Are they flexible with payment options like L/C, T/T, or PayPal?

Engaging with manufacturers who clearly list their capabilities and contact information, often including dedicated export departments for international clients, simplifies the purchasing process. Requesting quotes and samples before committing to large orders is a standard practice to validate product quality and supplier reliability.

Key Applications and Market Demand

The demand for 9-ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile is primarily driven by its indispensable role in the pharmaceutical industry, particularly in the synthesis of targeted cancer therapies. As a precursor to ALK inhibitors, it directly contributes to the development of treatments for specific types of cancer. Consequently, pharmaceutical companies and contract manufacturing organizations (CMOs) are significant end-users. The ongoing research into new drug candidates and the expansion of existing treatment portfolios mean that the market for such specialized intermediates remains robust. Buyers looking to secure their supply chain should actively seek out manufacturers offering this compound, ensuring a stable source for their critical synthesis needs.

When you need to buy this essential pharmaceutical intermediate, focusing on suppliers who understand the nuances of B2B chemical procurement will lead to a more efficient and successful transaction. They will be equipped to handle your inquiries regarding price, availability, and technical data.