The pharmaceutical industry's continuous quest for innovative treatments hinges on the reliable supply of high-quality chemical intermediates. Among these, 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone, identified by CAS number 1378387-81-5, stands out as a crucial component in sophisticated synthesis pathways. This guide aims to inform procurement managers and research scientists about this compound's significance and effective sourcing strategies.

Understanding the Intermediate: CAS 1378387-81-5

1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone is a key organic intermediate, recognized for its utility in crafting complex pharmaceutical molecules. Its chemical structure, a fluorene backbone featuring specific halogen and fluoro substitutions along with a chloroacetyl group, endows it with unique reactivity essential for targeted synthesis. Typically appearing as a white to light yellow powder or crystal, the compound is valued for its high purity, often exceeding 99.0%. This high assay is critical for ensuring the efficacy and safety of the final drug products, making it a preferred choice for pharmaceutical R&D and manufacturing.

Key Applications in Pharmaceutical Development

The primary role of 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone is as an intermediate for the synthesis of remipavir and other vital APIs. Its structural features allow for precise chemical modifications, enabling the development of drugs with specific pharmacological profiles. For companies involved in drug discovery and development, securing a dependable source for this intermediate is crucial for maintaining project timelines and ensuring product quality. Identifying a manufacturer with expertise in fluorene chemistry and stringent quality control is paramount.

Sourcing Effectively: The Manufacturer Advantage

When seeking to buy 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone, consider the benefits of sourcing directly from a specialized chemical manufacturer. Companies like NINGBO INNO PHARMCHEM CO.,LTD. offer advantages such as consistent quality, competitive pricing, and direct technical support. As a leading chemical supplier in China, we are committed to providing reliable access to high-purity intermediates. Our robust manufacturing processes ensure that we can meet the demands of both research laboratories and large-scale production facilities. We aim to be your trusted partner for this essential chemical.

Key Procurement Considerations

  • Product Specifications: Confirm purity (≥99.0%) and CAS number (1378387-81-5).
  • Manufacturer Reliability: Vet potential suppliers for their reputation and quality management systems.
  • Supply Chain Stability: Ensure the manufacturer can provide consistent and timely deliveries.
  • Technical Support: Access to expert advice can be invaluable for synthesis optimization.

NINGBO INNO PHARMCHEM CO.,LTD. is well-positioned to fulfill your requirements for 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone. We encourage all interested parties to contact us for quotes, samples, and detailed product information to support your pharmaceutical synthesis endeavors.