Procuring 10-Propargyl-10-deazaaminopterin: A Buyer's Guide
For professionals in the pharmaceutical and chemical industries, the consistent availability of high-quality raw materials and intermediates is the bedrock of successful product development and manufacturing. 10-Propargyl-10-deazaaminopterin, widely recognized as Pralatrexate (CAS 146464-95-1), is one such critical compound. Its role as a potent antifolate and its application in cancer therapy, particularly for peripheral T-cell lymphoma (PTCL), make it a sought-after intermediate.
This guide is designed to assist procurement managers, R&D scientists, and formulators in navigating the process of sourcing 10-Propargyl-10-deazaaminopterin. Understanding the key factors involved will ensure you can buy this compound efficiently and with confidence, securing a reliable supply for your needs.
Key Attributes of 10-Propargyl-10-deazaaminopterin:
Before you consider purchasing, it’s beneficial to understand the core characteristics of this molecule:
- Chemical Identity: CAS 146464-95-1, also known by synonyms such as Pralatrexate, PDX, and Folotyn.
- Mechanism: A potent inhibitor of dihydrofolate reductase (DHFR), crucial for DNA synthesis.
- Application: Primarily used as an API or intermediate in the treatment of PTCL and other cancers, and in related research.
- Physical Appearance: Typically appears as a white to light yellow powder.
What to Look for in a Supplier:
When you aim to buy 10-Propargyl-10-deazaaminopterin, focusing on the supplier's capabilities and offerings is essential:
- Manufacturing Expertise: Look for manufacturers with demonstrated experience in complex organic synthesis and a commitment to producing high-purity pharmaceutical intermediates. We, as a specialized manufacturer in China, pride ourselves on our advanced synthesis capabilities.
- Quality Assurance: A supplier must provide robust quality control, including detailed Certificates of Analysis (CoA) showing purity (often ≥98% or ≥99%) and characterization data. Adherence to international quality standards is a significant plus.
- Supply Reliability & Capacity: Ensure the manufacturer can meet your volume requirements, whether for small-scale R&D or large-scale commercial production. Clarify lead times and delivery schedules.
- Competitive Pricing: Obtain comprehensive quotations that reflect the quality and service provided. Comparing offers from different suppliers is a standard procurement practice, and we strive to offer competitive prices for bulk orders.
- Technical Support: Responsive customer service and technical assistance, including providing Safety Data Sheets (SDS), are indicators of a trustworthy partner.
Market Considerations:
The demand for Pralatrexate and its intermediates is driven by the evolving landscape of cancer treatment. By securing a relationship with a dependable 10-Propargyl-10-deazaaminopterin supplier, you can ensure your supply chain remains robust and efficient, allowing your research or manufacturing operations to proceed without interruption. We are dedicated to being that reliable partner for your chemical needs.
Perspectives & Insights
Molecule Vision 7
“This guide is designed to assist procurement managers, R&D scientists, and formulators in navigating the process of sourcing 10-Propargyl-10-deazaaminopterin.”
Alpha Origin 24
“Understanding the key factors involved will ensure you can buy this compound efficiently and with confidence, securing a reliable supply for your needs.”
Future Analyst X
“Key Attributes of 10-Propargyl-10-deazaaminopterin: Before you consider purchasing, it’s beneficial to understand the core characteristics of this molecule: Chemical Identity: CAS 146464-95-1, also known by synonyms such as Pralatrexate, PDX, and Folotyn.”