Navigating the procurement of specialized chemical intermediates can be a complex task, especially when precision and reliability are paramount. 2-Bromo-4-tert-butylpyridine, identified by its CAS registry number 50488-34-1, is one such compound that plays a critical role in various advanced chemical syntheses, particularly within the pharmaceutical and agrochemical sectors. For R&D scientists and purchasing managers, understanding how to effectively source this material is key to project success.

Key Attributes of 2-Bromo-4-tert-butylpyridine (CAS 50488-34-1)

This heterocyclic organic compound features a pyridine core substituted with a bromine atom and a tert-butyl group. Its chemical formula is C9H12BrN, with a molecular weight of 214.10. Key physical properties, such as a boiling point of approximately 243.6°C and a density of 1.293 g/cm³, provide essential data for handling and processing. The chemical reactivity is significantly influenced by the bromine atom, which serves as a reactive handle for various coupling reactions and substitutions, making it a highly valuable intermediate for organic chemists. The tert-butyl group offers steric bulk, which can impact reaction selectivity and product properties.

Where to Buy: Essential Considerations for Procurement

When looking to buy 2-Bromo-4-tert-butylpyridine, it is crucial to consider several factors to ensure you are obtaining a product that meets your exact specifications. Firstly, purity is often a critical parameter; suppliers typically offer this intermediate with a minimum purity of 97%. Secondly, sourcing from a reputable manufacturer or supplier, particularly one with a strong presence in China, can offer distinct advantages in terms of competitive pricing and large-scale availability. Many companies actively seek out manufacturers in China for these reasons.

For procurement managers, requesting detailed specifications, Certificates of Analysis (CoA), and Safety Data Sheets (SDS) is standard practice. These documents provide critical information on the product’s identity, purity, handling precautions, and physical properties. Engaging with suppliers who can provide these details promptly demonstrates their commitment to quality and transparency. When you purchase 2-Bromo-4-tert-butylpyridine, these documents are your first line of quality assurance.

Applications in Synthesis and Beyond

The primary utility of 2-Bromo-4-tert-butylpyridine lies in its function as a pharmaceutical intermediate. It is instrumental in the synthesis of complex molecules that form the basis of new medicines. Its specific structure allows chemists to build intricate molecular frameworks, leading to the development of novel APIs with targeted pharmacological activities. Furthermore, its application extends to the agrochemical industry, where it can be a precursor for advanced crop protection chemicals. As a chemical building block, it supports innovation in both sectors.

For those needing this material for research and development, smaller quantities are often available from specialized suppliers. For larger industrial needs, identifying a manufacturer with robust production capacity is essential. When you plan to purchase this chemical, consider the long-term supply reliability and the supplier's ability to scale up production as your needs grow.

In conclusion, 2-Bromo-4-tert-butylpyridine (CAS 50488-34-1) is a vital intermediate for chemical synthesis. By focusing on purity, supplier reliability, and comprehensive documentation, procurement professionals can effectively source this compound. For those looking to buy, exploring partnerships with established Chinese manufacturers offers a pathway to acquire this essential building block at competitive prices while ensuring quality for their critical projects.