For pharmaceutical manufacturers and R&D professionals, securing a consistent supply of high-quality intermediates is paramount. Methyl 5-formyl-2-methoxybenzoate (CAS 78515-16-9) is a critical building block, particularly for the synthesis of Eluxadoline. This article serves as a guide for procurement managers and research scientists looking to buy this essential compound.

Understanding the Importance of Purity

The efficacy and safety of the final Active Pharmaceutical Ingredient (API) are directly influenced by the purity of its intermediates. Methyl 5-formyl-2-methoxybenzoate, when used in Eluxadoline synthesis, requires stringent purity levels, typically above 97%. Impurities can lead to side reactions, reduced yields, and potentially compromise the final drug product. Therefore, when you buy methyl 5-formyl-2-methoxybenzoate, prioritize suppliers who provide detailed Certificates of Analysis (CoA) confirming high purity and assay results.

Key Considerations When Selecting a Supplier

As a potential buyer, you'll want to evaluate potential manufacturers and suppliers based on several factors:

  • Manufacturing Capabilities: Look for manufacturers with established expertise in producing pharmaceutical intermediates, particularly those with experience in complex organic synthesis. NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier of methyl 5-formyl-2-methoxybenzoate in China, known for its advanced production facilities.
  • Supply Chain Reliability: A dependable supply chain is crucial for uninterrupted production. Consider suppliers who can demonstrate consistent availability and timely delivery, whether for R&D quantities or bulk commercial orders.
  • Quality Control and Documentation: Ensure the supplier has robust quality control systems in place and can provide comprehensive documentation, including CoAs, Material Safety Data Sheets (MSDS), and potentially regulatory support for your filings.
  • Competitive Pricing: While quality is paramount, cost-effectiveness is also a key consideration. Compare pricing for methyl 5-formyl-2-methoxybenzoate from different reputable suppliers, looking for a balance between cost and quality assurance.
  • Technical Support: A supplier that offers technical support can be invaluable, especially when troubleshooting synthesis pathways or understanding product specifications.

The Role of Methyl 5-formyl-2-methoxybenzoate in Drug Development

Beyond its primary application in Eluxadoline synthesis, this chemical intermediate is also recognized for its utility in developing other therapeutic agents. For instance, it's used in the creation of peroxisome proliferator-activated receptor (PPAR) activators and PTP1B inhibitors. This versatility makes it a valuable compound for many pharmaceutical research and development pipelines.

How to Procure Methyl 5-formyl-2-methoxybenzoate

To initiate a purchase or request a quote, it’s advisable to contact the supplier directly. Providing essential details such as the CAS number (78515-16-9), required quantity, and desired purity will streamline the process. Many suppliers, like NINGBO INNO PHARMCHEM CO.,LTD., offer easy inquiry channels to buy methyl 5-formyl-2-methoxybenzoate, facilitating efficient transactions for businesses worldwide. Ensuring you work with an established pharmaceutical intermediates supplier will provide peace of mind and support for your product development goals.