4-Bromo-2-pentene, identified by the CAS number 1809-26-3, is a chemical compound that holds significant importance in the fields of organic synthesis and pharmaceutical development. This article aims to provide a comprehensive overview of its properties, methods of synthesis, and its crucial role as a chemical intermediate.

Chemical Identity and Physical Properties

The compound's chemical formula is C5H9Br, and its molecular weight is approximately 149.03 g/mol. A key characteristic of 4-Bromo-2-pentene is its appearance, often described as a white powder, though it exists as a liquid at room temperature with an estimated boiling point of 114.3°C. Its purity is typically high, often exceeding 99%, which is a critical factor for its use in sensitive chemical processes, particularly in the pharmaceutical industry. The compound's structure features an alkene functionality and a bromine atom, contributing to its reactive nature.

Synthesis Methods and Chemical Reactivity

The preparation of 4-Bromo-2-pentene can be achieved through several organic synthesis routes. Common methods include the addition of hydrogen bromide to specific pentene isomers or allylic bromination reactions. The control over regioselectivity and stereochemistry during synthesis is often a focus, as these factors can influence the compound's downstream applications. In terms of chemical reactivity, 4-Bromo-2-pentene is versatile. The bromine atom can be readily displaced by nucleophiles, enabling the formation of new C-Nu bonds. The double bond can undergo electrophilic addition reactions. These properties make it a valuable building block for constructing more complex organic molecules.

Key Applications and Market Relevance

The primary application of 4-Bromo-2-pentene is as an intermediate in the synthesis of pharmaceuticals. It is used in the production of Active Pharmaceutical Ingredients (APIs) and other fine chemicals. Its structural features allow for the introduction of specific chemical motifs that are vital for the biological activity of drug molecules. Beyond pharmaceuticals, it finds use in the broader fine chemical industry, contributing to the development of specialized materials and research chemicals. Companies looking to buy 4-bromo-2-pentene will find it available from various chemical suppliers, with pricing influenced by purity and order volume.

Sourcing and Quality Assurance

For researchers and manufacturers, ensuring the quality and consistent supply of 4-bromo-2-pentene is essential. Reputable suppliers provide detailed specifications, including CAS numbers and purity levels, alongside handling and safety information. The market for such intermediates is competitive, with a focus on providing high-purity materials at reasonable prices. Understanding the typical price range and the reliability of different 4-bromo-2-pentene suppliers is crucial for efficient procurement and project success.

In summary, 4-Bromo-2-pentene (CAS 1809-26-3) is a fundamental chemical intermediate whose properties and reactivity are key to advancements in pharmaceutical synthesis and fine chemical production.