The pharmaceutical industry relies heavily on a robust supply of high-quality intermediates to synthesize life-saving drugs. Among these, 3-Pyridinesulfonyl Chloride Hydrochloride (CAS 16133-25-8) plays a significant role, particularly as a building block for advanced APIs. Understanding its utility and how to procure it effectively is vital for R&D scientists, formulation chemists, and procurement specialists. This article delves into the importance of this chemical and offers insights for businesses looking to buy from reliable manufacturers.

Understanding Pyridine-3-sulfonyl Chloride Hydrochloride

Pyridine-3-sulfonyl Chloride Hydrochloride (CAS 16133-25-8) is recognized for its chemical structure and reactivity, making it a valuable component in complex organic synthesis pathways. As a derivative of pyridine and a sulfonyl chloride, it possesses functional groups that enable it to participate in key reactions required for forming more intricate molecular structures. Its primary application lies in its use as a pharmaceutical intermediate, contributing to the development and manufacturing of various medicinal compounds.

Key Applications in Drug Development

The compound's primary claim to fame in the pharmaceutical sector is its role in the synthesis of vonoprazan fumarate. Vonoprazan is a P-CAB (Potassium-Competitive Acid Blocker) used to treat acid-related disorders. The successful synthesis of such targeted therapies relies on the availability of high-purity intermediates like Pyridine-3-sulfonyl Chloride Hydrochloride. Its consistent supply ensures that manufacturing processes can proceed without interruption, meeting the growing demand for effective treatments.

Procuring High-Quality Intermediates

For companies aiming to purchase Pyridine-3-sulfonyl Chloride Hydrochloride, selecting the right supplier is paramount. When sourcing this chemical, especially from manufacturers in China, focus on suppliers that offer:

  • Guaranteed Purity: Look for products with a minimum purity specification, typically 98% or higher, backed by a Certificate of Analysis (CoA).
  • Consistent Supply: Ensure the manufacturer can provide a stable and reliable supply chain, capable of meeting your production volumes from R&D to commercial scale.
  • Competitive Pricing: Obtain quotes from multiple manufacturers to compare pricing and find the best value without compromising on quality.
  • Regulatory Compliance: Verify that the supplier adheres to relevant industry standards and regulations.

The Manufacturer's Advantage

Partnering directly with a manufacturer offers distinct advantages, including potentially better pricing, direct communication, and greater transparency in the supply chain. Companies specializing in fine chemicals and pharmaceutical intermediates are often equipped with the expertise and infrastructure to meet stringent pharmaceutical requirements. These manufacturers can often provide custom synthesis and packaging options tailored to specific project needs.

Conclusion

Pyridine-3-sulfonyl Chloride Hydrochloride (CAS 16133-25-8) is a critical chemical intermediate that empowers the development of modern pharmaceuticals. By understanding its applications and diligently selecting a reliable manufacturer and supplier, businesses can ensure they have access to the high-purity materials necessary for successful drug synthesis. If you're looking to buy this essential compound, prioritize quality, consistency, and a strong supplier relationship for optimal results in your pharmaceutical manufacturing endeavors.