For any pharmaceutical research and development team, securing a reliable supply of critical intermediates is paramount. One such essential compound is 1,3-Dichloro-4-fluorobenzene, known by its CAS number 1435-48-9. This article aims to guide procurement managers in understanding the key considerations when sourcing this vital chemical building block from manufacturers and suppliers, particularly those based in China, ensuring both quality and cost-effectiveness.

Understanding 1,3-Dichloro-4-fluorobenzene (CAS 1435-48-9)

1,3-Dichloro-4-fluorobenzene is a halogenated aromatic compound with the molecular formula C6H3Cl2F. Its specific chemical structure makes it an indispensable intermediate in the synthesis of numerous active pharmaceutical ingredients (APIs), including certain broad-spectrum antibiotics. Its physical properties, such as a melting point of -23 °C and a boiling point of 172-174 °C, are crucial for its handling and application in various chemical processes. When procurement managers are looking to buy this material, understanding these basic specifications is the first step.

Key Considerations for Procurement Managers

When a procurement manager seeks to purchase 1,3-Dichloro-4-fluorobenzene, several factors should be prioritized to ensure a smooth and successful acquisition:

  • Purity and Quality Assurance: The efficacy and safety of the final pharmaceutical product are directly dependent on the purity of its intermediates. It is essential to partner with suppliers who can provide detailed Certificates of Analysis (CoA) and have robust quality control systems in place. Look for specifications like >99% purity for critical applications.
  • Supplier Reliability and Lead Times: Consistent supply and adherence to delivery schedules are non-negotiable in the pharmaceutical industry. A strong manufacturer in China can often offer competitive pricing and manageable lead times, but it's important to vet their production capacity and logistics capabilities.
  • Regulatory Compliance: Ensure that the supplier can provide necessary documentation for regulatory purposes, such as MSDS (Material Safety Data Sheet) and compliance with international chemical regulations.
  • Price and Value Proposition: While cost is a significant factor, it should be balanced against quality and reliability. A slightly higher price for a guaranteed pure and consistently supplied product can prevent costly production delays and quality issues down the line. Always inquire about the best price for your required volume.

Navigating the Chinese Market

China has emerged as a global powerhouse for chemical manufacturing, offering a vast array of intermediates like 1,3-Dichloro-4-fluorobenzene. For procurement managers, identifying reputable Chinese suppliers and manufacturers is key. Factors to consider include:

  • Established export experience.
  • Customer testimonials and industry reputation.
  • Certifications such as ISO.
  • Proximity to major shipping ports for efficient logistics.

By conducting thorough due diligence, procurement managers can confidently select a Chinese supplier that meets their specific needs for 1,3-Dichloro-4-fluorobenzene (CAS 1435-48-9). Partnering with a knowledgeable and quality-focused manufacturer ensures that your R&D and production pipelines remain robust and efficient.

If you are looking to buy high-quality 1,3-Dichloro-4-fluorobenzene, consider reaching out to established chemical suppliers in China. They can provide competitive quotes and ensure you receive a product that meets your exacting standards, ultimately contributing to the success of your pharmaceutical development projects.