Sourcing Dibenz[b,e]oxepin-11(6H)-one: A Guide for Pharmaceutical Buyers
For procurement managers and R&D scientists in the pharmaceutical industry, sourcing critical intermediates like Dibenz[b,e]oxepin-11(6H)-one (CAS 4504-87-4) is a cornerstone of successful drug development and manufacturing. As a key intermediate in the synthesis of doxepin, understanding where and how to buy this compound is paramount for ensuring product quality, supply chain stability, and cost-effectiveness.
Dibenz[b,e]oxepin-11(6H)-one, a pale yellow solid with a CAS number of 4504-87-4, is recognized for its high purity, often exceeding 98% or 99%. This level of purity is non-negotiable for pharmaceutical applications, as impurities can significantly impact the efficacy and safety of the final active pharmaceutical ingredient (API). Therefore, when looking to purchase this compound, prioritizing suppliers who can consistently provide certified high-purity material is essential.
When considering a manufacturer or supplier, particularly from China, several factors come into play. Firstly, investigate their production capabilities and quality control processes. Do they have ISO certifications? Can they provide detailed Certificates of Analysis (COA) for each batch, including data on purity, physical form, and any relevant impurities? A reputable supplier will readily share this information.
Secondly, evaluate their supply chain reliability. For a critical intermediate like Dibenz[b,e]oxepin-11(6H)-one, consistent availability and on-time delivery are crucial. Manufacturers with significant production capacities and established logistics networks are better positioned to meet the demands of pharmaceutical companies, whether for R&D quantities or large-scale commercial production.
Thirdly, the price of Dibenz[b,e]oxepin-11(6h)-one is naturally a significant consideration. Comparing quotes from multiple trusted suppliers can help secure competitive pricing without compromising on quality. Don't hesitate to inquire about bulk discounts or long-term supply agreements.
Dibenz[b,e]oxepin-11(6H)-one plays a pivotal role as a precursor in the synthesis of doxepin, a tricyclic antidepressant. Its chemical structure makes it an ideal starting point for building the complex molecular architecture required for this therapeutic agent. Beyond doxepin, this intermediate may also find applications in the synthesis of other related pharmaceutical compounds or in chemical research exploring novel heterocycles.
For those looking to buy Dibenz[b,e]oxepin-11(6H)-one, engaging with established chemical suppliers in China offers access to a vast manufacturing base. Companies specializing in fine chemical intermediates are well-equipped to handle the synthesis and export of such compounds. By conducting thorough due diligence and establishing clear communication channels, pharmaceutical buyers can secure a dependable source for this vital chemical building block. Ultimately, a strategic partnership with a quality-focused supplier ensures the integrity of your production pipeline.
Perspectives & Insights
Future Origin 2025
“This level of purity is non-negotiable for pharmaceutical applications, as impurities can significantly impact the efficacy and safety of the final active pharmaceutical ingredient (API).”
Core Analyst 01
“Therefore, when looking to purchase this compound, prioritizing suppliers who can consistently provide certified high-purity material is essential.”
Silicon Seeker One
“When considering a manufacturer or supplier, particularly from China, several factors come into play.”