For procurement managers and research scientists in the pharmaceutical and biotechnology sectors, identifying reliable sources for critical chemical intermediates is paramount. Fmoc-Sar-OH (CAS: 77128-70-2), a specialized N-methylglycine derivative, is one such compound that plays a vital role in advanced peptide synthesis. As a premier manufacturer and supplier of fine chemicals in China, we aim to provide clarity on the importance of sourcing this high-value product and how our capabilities meet industry demands.

Fmoc-Sar-OH, also known as N-Fmoc-N-methylglycine, is a protected amino acid derivative widely used in the synthesis of peptides. The Fmoc protecting group is standard in modern peptide chemistry, ensuring controlled, step-by-step assembly of amino acid sequences. The inclusion of a methyl group on the glycine nitrogen atom is what distinguishes sarcosine derivatives like Fmoc-Sar-OH. This structural modification is known to enhance the metabolic stability and often the conformational properties of the peptides in which it is incorporated. This makes it a sought-after ingredient for researchers developing peptide-based therapeutics, diagnostics, and advanced biomaterials.

When considering a purchase, understanding the specifications is crucial. Fmoc-Sar-OH presents as a white powder, with a molecular formula of C18H17NO4 and a molecular weight of 311.33. Its defined melting point and chemical stability are key indicators of quality. For businesses looking to buy Fmoc-Sar-OH, particularly in bulk quantities, partnering with a manufacturer that guarantees high purity (typically ≥95% via HPLC) and consistent batch-to-batch quality is essential. We, as a leading chemical supplier in China, pride ourselves on meeting these stringent requirements.

The primary application of Fmoc-Sar-OH lies in its use as a building block in solid-phase peptide synthesis (SPPS). It allows for the precise incorporation of sarcosine residues into peptide sequences, enabling the creation of peptides with unique pharmacological profiles. This makes it an indispensable component in drug discovery pipelines, particularly for peptidomimetics and modified peptides. For any R&D team, securing a dependable supply chain for such specialized reagents is a strategic advantage. We offer competitive pricing and reliable delivery, making us an ideal partner for your procurement needs.

We encourage research institutions and pharmaceutical companies to consider our manufacturing capabilities for your Fmoc-Sar-OH requirements. By choosing us as your supplier, you gain access to a high-quality product directly from a China-based manufacturer, ensuring efficiency and cost-effectiveness. Contact us today to request a quote or sample of our Fmoc-Sar-OH and discuss how we can support your ongoing research and development projects.