For procurement managers and R&D scientists in the pharmaceutical and biotech sectors, sourcing high-quality chemical intermediates is paramount. N-Benzyloxycarbonyl-L-tryptophan Methyl Ester, often abbreviated as Z-Trp-OMe (CAS: 2717-76-2), stands out as a crucial building block in peptide synthesis and the development of Active Pharmaceutical Ingredients (APIs). Understanding its key attributes and how to procure it effectively from reputable manufacturers is essential for project success.

Understanding Z-Trp-OMe: Properties and Significance

N-Benzyloxycarbonyl-L-tryptophan Methyl Ester is characterized by its chemical formula C20H20N2O4 and a molecular weight of 352.384. It typically appears as a white powder, with stringent purity requirements often set at ≥98%. This compound's significance lies in its protected tryptophan structure, where the benzyloxycarbonyl (Cbz or Z) group protects the alpha-amino group, and the methyl ester protects the carboxyl group. This protection strategy is fundamental in peptide synthesis, preventing unwanted reactions and ensuring that peptide bond formation occurs at the correct sites. Its role as a pharmaceutical intermediate makes it indispensable for synthesizing complex peptides and drug molecules.

Key Considerations for Purchasing Z-Trp-OMe

When looking to buy N-Benzyloxycarbonyl-L-tryptophan Methyl Ester, several factors should guide your selection:

  • Purity: Always prioritize suppliers who guarantee a purity of 98% or higher. This directly impacts the success and reproducibility of your synthesis, especially in regulated environments.
  • Supplier Reliability: Partnering with established manufacturers or suppliers in China known for consistent quality and dependable supply chains is crucial. Look for companies with clear product specifications and good customer feedback.
  • Application Suitability: Confirm that the grade of Z-Trp-OMe meets your specific application needs, whether it’s for standard peptide synthesis, chiral drug development, or biochemical research.
  • Pricing and Lead Times: Obtain quotes from multiple suppliers to ensure competitive pricing and understand lead times to manage your project timelines effectively.

Finding a Trusted Manufacturer in China

China has emerged as a significant global hub for chemical manufacturing, offering a wide array of pharmaceutical intermediates. To secure a reliable supply of N-Benzyloxycarbonyl-L-tryptophan Methyl Ester, consider manufacturers who:

  • Provide detailed Certificates of Analysis (CoA) for their products.
  • Offer technical support and are responsive to inquiries.
  • Have a transparent manufacturing process and adhere to international quality standards.
  • Demonstrate a commitment to sustainable and ethical production practices.

By focusing on these aspects, procurement managers can confidently purchase Z-Trp-OMe, ensuring that their research and manufacturing processes are supported by high-quality chemical intermediates. For those seeking to buy this vital compound, exploring options from reputable Chinese manufacturers will yield the best results.