In the dynamic field of pharmaceutical research and chemical synthesis, having access to reliable, high-purity intermediates is paramount. N-Benzyloxycarbonyl-L-tryptophan Methyl Ester, widely known by its abbreviation Z-Trp-OMe (CAS: 2717-76-2), stands out as a critical component for peptide synthesis and the creation of various pharmaceutical compounds. This article highlights the importance of this versatile amino acid derivative and guides you on procuring it effectively from trusted suppliers.

The Significance of Z-Trp-OMe in Peptide Synthesis

Tryptophan, an essential amino acid, is vital in many biological processes but can be challenging to incorporate into synthetic peptides due to the reactivity of its indole side chain. Z-Trp-OMe addresses this by providing a protected form of tryptophan. The N-benzyloxycarbonyl (Cbz or Z) group shields the alpha-amino group, and the methyl ester protects the carboxyl group. This dual protection ensures controlled coupling reactions, preserves stereochemistry, and ultimately leads to higher yields and purity in synthesized peptides. Its chemical formula is C20H20N2O4, with a molecular weight of 352.384, typically supplied as a white powder with a purity of ≥98%.

Why Choose Z-Trp-OMe for Your Projects?

Researchers and procurement specialists choose Z-Trp-OMe for several key advantages:

  • Controlled Reactivity: The protecting groups allow for selective manipulation during complex synthesis, minimizing side reactions.
  • High Purity: A purity of ≥98% ensures reliable and reproducible results in your laboratory or manufacturing processes.
  • Versatility: It's an excellent building block for a wide range of peptides used in pharmaceuticals, diagnostics, and research.
  • Cost-Effective Sourcing: Reliable manufacturers, particularly those in China, offer competitive pricing, making it an accessible intermediate for many projects.

Procuring Z-Trp-OMe Effectively

When you need to buy N-Benzyloxycarbonyl-L-tryptophan Methyl Ester, focus on suppliers that offer:

  • Guaranteed Purity: Always look for the ≥98% purity mark.
  • Consistent Quality: Ensure the supplier has robust quality control and can provide Certificates of Analysis (CoA).
  • Reliable Supply: Partner with manufacturers that can meet your volume needs and ensure timely delivery.
  • Technical Support: Access to expert advice can be invaluable when integrating new chemical intermediates into your workflow.

By understanding the properties and benefits of Z-Trp-OMe and choosing your suppliers wisely, you can ensure the success of your peptide synthesis and pharmaceutical development endeavors. For those looking to source this crucial intermediate, exploring options from reputable Chinese manufacturers will provide both quality and value.