In the dynamic fields of pharmaceutical research and development (R&D) and large-scale manufacturing, access to high-quality chemical intermediates is paramount. Thiophene-2-carboxylic acid, identified by its CAS number 527-72-0, is a compound of significant importance, widely utilized as a building block for novel therapeutics and established drug compounds. This article highlights its essential properties and discusses how R&D professionals and procurement managers can effectively source this vital chemical from reliable manufacturers.

Understanding Thiophene-2-carboxylic Acid: Chemical Identity and Properties

Thiophene-2-carboxylic acid, also known as 2-thenoic acid, is an organic chemical characterized by its white crystalline powder appearance. Its molecular formula is C5H4O2S, with a molecular weight of 128.15 g/mol. A critical specification for its use, especially in pharmaceutical applications, is its high purity, often exceeding 99%. The compound's melting point, typically in the range of 125-127 °C, confirms its solid state under normal laboratory conditions. These well-defined physical and chemical properties make it a dependable intermediate for complex synthetic processes.

Role in Pharmaceutical Research and Manufacturing

The thiophene ring is a prevalent structural motif in many pharmacologically active compounds, contributing to their efficacy and pharmacokinetic profiles. Thiophene-2-carboxylic acid serves as an accessible precursor for introducing this important heterocyclic system into drug candidates. It is instrumental in the synthesis of various APIs, enabling researchers to explore new therapeutic avenues and optimize existing drug formulations. For manufacturers, a consistent and reliable supply of this high-purity intermediate is crucial for uninterrupted production cycles and the consistent quality of finished pharmaceutical products.

Sourcing Strategies: Finding Reliable Suppliers in China

When seeking to buy Thiophene-2-carboxylic acid, leveraging China's extensive chemical manufacturing capabilities offers distinct advantages, including competitive pricing and a broad range of suppliers. Procurement specialists should prioritize manufacturers with established quality control systems and a demonstrated history of producing high-purity pharmaceutical intermediates. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are recognized for their commitment to quality and reliability. Key steps in the sourcing process include requesting product samples for quality verification, obtaining detailed Certificates of Analysis (CoA), and inquiring about bulk order pricing and lead times.

Key Considerations for R&D and Procurement Teams

For pharmaceutical R&D teams, having access to Thiophene-2-carboxylic acid allows for timely experimentation and the development of new synthetic routes. For manufacturing operations, securing a stable supply chain from a trusted partner is essential for meeting production demands efficiently and cost-effectively. When engaging with suppliers, clarity on specifications, packaging, and delivery terms is vital. Understanding the typical market price for Thiophene-2-carboxylic acid will also assist in budgeting and strategic purchasing. A strong supplier relationship ensures the consistent quality and availability needed for critical pharmaceutical projects.

NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier specializing in high-quality Thiophene-2-carboxylic acid (CAS: 527-72-0). We are dedicated to supporting the pharmaceutical industry with reliable intermediates at competitive prices. Contact us today to inquire about purchasing Thiophene-2-carboxylic acid and to receive a prompt quotation.