Tolvaptan, identified by the CAS number 150683-30-0, is a compound of significant interest in the pharmaceutical and medical research sectors. Its specific chemical structure and properties lend themselves to important therapeutic applications, primarily in the management of hyponatremia, a condition characterized by low serum sodium levels. Understanding its chemical profile is fundamental for researchers, manufacturers, and clinicians.

The chemical identity of Tolvaptan is characterized by its molecular formula, C26H25ClN2O3, and a molecular weight of 448.94. Typically appearing as a white to off-white powder, it possesses a defined melting point range, usually between 219-230°C, indicative of its crystalline structure. Its solubility characteristics, particularly in solvents like DMSO, are important for its use in laboratory settings and potentially in the formulation of drug products. These details form the basis for its identification and handling in various scientific contexts.

Medically, Tolvaptan is recognized for its role as a selective vasopressin V2 receptor antagonist. This pharmacological action allows it to selectively promote the excretion of free water from the body, which is essential for increasing serum sodium levels in patients with hyponatremia. This is particularly beneficial for individuals suffering from conditions such as congestive heart failure, liver cirrhosis, and SIADH, where fluid retention contributes to the imbalance of electrolytes. The therapeutic decision to treat hyponatremia with Tolvaptan is based on its efficacy in such complex cases.

The application of Tolvaptan in clinical practice necessitates adherence to critical Tolvaptan safety precautions. These include the careful monitoring of serum sodium levels during treatment initiation and titration to prevent rapid correction, which can lead to serious neurological consequences like osmotic demyelination syndrome. Manufacturers and researchers seeking this compound should prioritize sourcing from a dependable Tolvaptan API supplier in China to ensure they receive a high-quality pharmaceutical intermediate that meets all required specifications. This diligence in sourcing and application ensures the compound's potential is realized safely and effectively.