Navigating the landscape of chemical intermediates requires a thorough understanding of their properties and sourcing mechanisms. 1-Benzyl-4-hydroxypiperidine (CAS 4727-72-4) is a prime example of a critical chemical that serves diverse applications, especially within the pharmaceutical sector. This article aims to shed light on its key attributes, its role in synthesis, and how procurement professionals can best secure a reliable supply chain for this essential compound.

Core Characteristics of 1-Benzyl-4-hydroxypiperidine

The compound is typically described as a white to off-white crystalline powder, with a melting point usually falling between 61-63°C. Its molecular formula, C12H17NO, and molecular weight of 191.27 g/mol are standard identification markers. The presence of both a hydroxyl group and a tertiary amine within its structure makes it a valuable intermediate for further chemical transformations. It is frequently used in the synthesis of more complex molecules, finding significant application as a precursor in the pharmaceutical industry for developing analgesics and other neurologically active compounds.

Synthesis and Application Insights

The synthesis of 1-Benzyl-4-hydroxypiperidine often involves reactions starting from simpler piperidine derivatives. Its utility as a pharmaceutical intermediate is its most prominent application, where it contributes to the development of new drug candidates by providing a core structural motif. Beyond pharmaceuticals, it can also be employed in academic research for exploring new reaction methodologies or synthesizing novel organic compounds with potential applications in material science or agrochemicals. For those looking to buy this compound for research or production, understanding its purity (typically ≥98.0%) and physical state is essential for successful integration into their processes.

Procurement Strategies for Buyers

Securing a consistent and high-quality supply of 1-Benzyl-4-hydroxypiperidine is a priority for many R&D departments and manufacturing units. When looking to purchase this chemical, it is advisable to partner with established manufacturers and suppliers. Companies in regions known for chemical production, such as China, often provide competitive pricing and a wide availability of such intermediates. Buyers are encouraged to request detailed specifications, inquire about bulk order discounts, and ensure that their chosen supplier has robust quality control systems in place. Obtaining quotes from multiple verified suppliers will help ensure you are getting the best value and a reliable supply for your ongoing chemical needs.