In the vast landscape of fine chemicals, 2,3-Dihydrobenzofuran-5-carbaldehyde (CAS 55745-70-5) holds a significant position, primarily as a versatile intermediate in organic synthesis and pharmaceutical manufacturing. This article provides a detailed look at its properties, applications, and how to best source it from trusted manufacturers and suppliers.

Chemically, 2,3-Dihydrobenzofuran-5-carbaldehyde is an aromatic aldehyde. Its molecular formula is C9H8O2, with a molecular weight of 148.16 g/mol. The presence of both the fused heterocyclic dihydrobenzofuran ring system and the reactive aldehyde group makes it a valuable synthon. Typically appearing as a colorless to pale yellow liquid or solid depending on purity and storage conditions, its physical state and properties are important considerations for handling and application. Its boiling point, approximately 277.5 °C at 760 mmHg, indicates its relative thermal stability.

The primary application of this compound is its use as a key intermediate in the synthesis of pharmaceuticals. A notable example is its role in the production of Ramelteon, a medication used to treat insomnia. The aldehyde group allows for specific reactions to build the complex structure of the final drug molecule. Beyond pharmaceuticals, its utility as a building block in general organic synthesis is also recognized, enabling the creation of novel compounds for research and development purposes.

For those looking to buy 2,3-Dihydrobenzofuran-5-carbaldehyde, it is imperative to source from reputable manufacturers and suppliers. Key considerations include purity levels, typically specified as ≥96.0% or ≥98.0% (GC), as well as the consistency of supply. Suppliers often provide detailed specifications, including density and flash point, which are important for safety and process optimization.

When seeking quotes for 2,3-Dihydrobenzofuran-5-carbaldehyde, consider suppliers based in China, as they are often major manufacturers with competitive pricing. It’s advisable to compare offers from several companies to ensure you are getting the best value for your procurement needs. Understanding the supplier’s documentation support, such as CoAs and MSDS, is also essential. Whether you are a researcher needing small quantities or a manufacturer requiring bulk supply, a reliable supplier ensures product quality and timely delivery, facilitating your project's success.