For professionals in the chemical and pharmaceutical sectors, a thorough understanding of product specifications is crucial for informed purchasing decisions. 4-Fluorophenylacetonitrile (CAS 459-22-3) is a chemical intermediate of significant importance, particularly in the synthesis of pharmaceutical compounds. This article aims to provide clarity on its key attributes and guide procurement specialists on how to efficiently source it from reliable vendors.

The chemical identity of 4-Fluorophenylacetonitrile is defined by its CAS number, 459-22-3, and its molecular formula, C8H6FN. Physically, it is described as a clear colorless to light yellow liquid. For critical applications in pharmaceutical manufacturing, the assay is a paramount specification, typically requiring a minimum purity of 98.0%. Higher purity grades may also be available, depending on the manufacturer and specific customer requirements. Adherence to recognized quality standards, such as USP, BP, EP, and FCC, is often a non-negotiable requirement for procurement managers aiming for compliance and product excellence.

When considering where to buy 4-Fluorophenylacetonitrile, the competitive landscape of chemical suppliers, especially in China, offers numerous options. However, discerning the best supplier involves evaluating more than just the product listing. A proactive approach includes verifying the manufacturer's credentials, such as GMP or ISO certifications, and understanding their production capabilities. The price of 4-Fluorophenylacetonitrile can vary based on purity, order volume, and current market conditions, making it essential to obtain multiple quotes.

The utility of 4-Fluorophenylacetonitrile extends to its role as a key intermediate in the synthesis of drugs like Aprepitant, which is vital for managing nausea and vomiting in cancer patients. Therefore, ensuring a stable and dependable supply is critical for uninterrupted production cycles. Packaging, often in 200kg drums, needs to be suitable for safe transport and storage, aligning with logistical requirements for B2B shipments.

For procurement professionals, the process of sourcing chemical intermediates like 4-Fluorophenylacetonitrile can be streamlined by leveraging online platforms and direct communication channels with manufacturers. Accessing product information, requesting samples, and obtaining timely quotes are integral steps in establishing a strong supplier relationship. By focusing on quality specifications and reliable sourcing partners, businesses can ensure the integrity and efficiency of their pharmaceutical supply chain.