In the field of specialized organic chemistry, certain molecules serve as foundational elements for critical applications, particularly within the pharmaceutical sector. One such compound is a-D-Glucofuranose, 1,2-O-(1-Methylethylidene)-3-O-(phenylmethyl)-, identified by its CAS number 22529-61-9. This article provides an in-depth look at its chemical characteristics, primary uses, and considerations for procurement by research institutions and manufacturing companies.

The chemical identity of a-D-Glucofuranose, 1,2-O-(1-Methylethylidene)-3-O-(phenylmethyl)- is defined by its molecular formula, C16H22O6, and a molecular weight of 310.34. This compound is a derivative of D-glucofuranose, modified with an isopropylidene group at the 1,2-O positions and a benzyl (phenylmethyl) group at the 3-O position. These protective groups are essential for directing reactivity in complex synthetic pathways. Physically, it is often encountered as an oil, typically described as clear, colorless to yellow, with properties like a density of 1.29 g/cm³ and a high boiling point, indicating its relative stability under standard laboratory conditions. These features are critical for its successful implementation in chemical processes.

The primary application of this specific glucofuranose derivative lies in its function as a key intermediate in the synthesis of Fondaparinux Sodium. Fondaparinux Sodium is a potent anticoagulant medication, and its complex structure necessitates the use of highly specific building blocks during its manufacturing. The compound 22529-61-9 provides the necessary stereochemical and functional group arrangement required to efficiently construct the Fondaparinux molecule, underscoring its importance in pharmaceutical intermediate manufacturing. This role makes it a valuable commodity for companies specializing in the production of active pharmaceutical ingredients (APIs).

For researchers and industrial chemists, understanding where to buy a-D-Glucofuranose, 1,2-O-(1-Methylethylidene)-3-O-(phenylmethyl)- is paramount. Numerous suppliers globally offer this chemical, with many reputable manufacturers located in China, ensuring accessibility for diverse project needs. When considering a purchase, it is important to verify the purity (commonly 97% or higher), the available quantities (from research-scale grams to bulk kilograms), and the supplier's adherence to quality standards. The ability to source this intermediate reliably supports ongoing research and development efforts in drug discovery and refinement of synthetic processes.

In essence, a-D-Glucofuranose, 1,2-O-(1-Methylethylidene)-3-O-(phenylmethyl)- is more than just a chemical compound; it is a vital enabler for critical pharmaceutical production. Its well-defined chemical properties and established role as an intermediate for Fondaparinux Sodium solidify its position in advanced organic synthesis. Researchers and manufacturers seeking this specialty chemical can rely on a global network of suppliers to meet their requirements for high-quality building blocks.