The continuous evolution of chemical synthesis, particularly in the pharmaceutical sector, hinges on the availability and intelligent use of specialized intermediates. Protected carbohydrate derivatives, such as a-D-Glucofuranose, 1,2-O-(1-Methylethylidene)-3-O-(phenylmethyl)- (CAS 22529-61-9), represent a critical frontier in this domain. These molecules offer unique structural advantages that facilitate the construction of complex therapeutic agents and novel chemical entities.

At its core, a-D-Glucofuranose, 1,2-O-(1-Methylethylidene)-3-O-(phenylmethyl)- is a strategically modified carbohydrate. Its molecular formula, C16H22O6, and molecular weight of 310.34 reflect its sophisticated structure, which includes isopropylidene and benzyl protecting groups. These groups are crucial for selectively directing chemical reactions, preventing unwanted side reactions, and ensuring the correct stereochemical outcome during synthesis. The compound typically presents as an oil, often a clear, colorless to yellow liquid, making it amenable to various liquid-phase reaction conditions. Its density is noted to be around 1.29 g/cm³.

The primary driver for the demand of this glucofuranose derivative is its indispensable role as an intermediate in the synthesis of Fondaparinux Sodium. This synthetic anticoagulant is a testament to the power of medicinal chemistry, and its production relies on precursors that possess the precise structural features of compounds like 22529-61-9. By providing a pre-organized chiral framework with appropriate protecting groups, it significantly streamlines the manufacturing process for this vital medication, thereby supporting pharmaceutical intermediate manufacturing efforts worldwide.

For chemical companies and research institutions, understanding the sourcing landscape for such specialized materials is vital. Reliable suppliers, including many established manufacturers in China, offer a-D-Glucofuranose, 1,2-O-(1-Methylethylidene)-3-O-(phenylmethyl)- with guaranteed purity levels, often exceeding 97%. This accessibility ensures that research and development projects, as well as large-scale production runs, can proceed without interruption. The ability to buy this chemical in various lot sizes, from grams for initial exploration to bulk quantities for industrial production, is a key factor for strategic procurement.

The utility of this protected glucofuranose derivative is not limited to its current primary application. Its structure makes it a valuable synthon for chemists exploring new molecular architectures in areas beyond pharmaceuticals, such as in the development of new materials or advanced biochemical probes. The controlled reactivity offered by its protecting groups makes it an excellent starting point for creating diverse and complex molecules. Thus, for professionals at the cutting edge of chemical synthesis and research, having access to and understanding the applications of these advanced intermediates is essential for driving innovation forward.