Ethyl 5-Bromobenzofuran-2-Carboxylate (CAS: 84102-69-2) is a fine chemical that plays a significant role in various synthetic pathways, particularly in medicinal chemistry and the development of novel organic compounds. As a brominated benzofuran derivative, it offers unique reactivity that makes it a valuable building block for complex molecules.

Physically, this compound presents as a light yellow solid powder, with a specified melting point range of 60-62°C. Its molecular formula is C11H9BrO3, and its molecular weight is approximately 269.09 g/mol. The presence of the bromine atom at the 5-position of the benzofuran ring is crucial, as it enhances the compound's utility in cross-coupling reactions and other synthetic transformations. This makes it an attractive intermediate for researchers looking to introduce specific functionalities into their target molecules.

The synthesis of Ethyl 5-Bromobenzofuran-2-Carboxylate typically involves bromination of appropriate benzofuran precursors followed by esterification. One common route might involve the esterification of 5-bromobenzofuran-2-carboxylic acid with ethanol in the presence of an acid catalyst. The efficiency and purity achieved in these synthetic steps are vital for the compound's subsequent applications. For those seeking to purchase this chemical, identifying a manufacturer that masters these synthetic processes and can consistently deliver high purity (≥99%) is paramount.

Its primary application lies as an intermediate in the synthesis of pharmaceuticals. Notably, it is used in the production of Veratrazodone hydrochloride, a compound explored for its therapeutic potential. This application underscores the importance of sourcing high-quality intermediates that meet strict regulatory and purity standards. Procurement managers often look for 'pharmaceutical intermediate price' and 'buy Ethyl 5-Bromobenzofuran-2-Carboxylate' to secure cost-effective and reliable supplies.

Beyond pharmaceuticals, its utility as a building block in organic synthesis is widely recognized. It can be employed in the creation of new benzofuran-2-carboxylate derivatives, which may possess diverse biological activities or find use in material science. When considering purchasing this compound, it is advisable to engage with suppliers who can provide comprehensive technical documentation, such as specifications and safety data sheets, and who have a proven track record in chemical manufacturing. For businesses sourcing internationally, China often represents a strong market for such fine chemical intermediates due to its extensive chemical industry infrastructure.

In conclusion, Ethyl 5-Bromobenzofuran-2-Carboxylate is a critical component in modern chemical synthesis. Its well-defined properties and broad applications make it a valuable asset for researchers and manufacturers. Understanding its synthesis and sourcing reliable suppliers, particularly in regions like China, are key considerations for any organization looking to leverage this important chemical intermediate.