Potassium channels are fundamental to cellular function, playing critical roles in regulating membrane potential, cellular excitability, and signal transduction. The two-pore domain potassium (K2P) channel subfamily, which includes channels like TASK-1 (KCNK3), is particularly important for maintaining resting membrane potential and influencing neuronal excitability. Disruptions in K2P channel function have been linked to various neurological and cardiovascular disorders, making them attractive targets for pharmacological intervention.

For researchers focused on these critical channels, selective modulators are essential. ML365 (CAS: 947914-18-3) has emerged as a highly valuable tool due to its potent and selective inhibitory action against the TASK-1 channel. With an IC50 of 4 nM, ML365 provides a precise mechanism to probe the specific functions of TASK-1 in complex biological systems. Its high selectivity means it has minimal impact on other potassium channel subtypes, offering a cleaner experimental profile compared to less specific agents.

As a leading manufacturer and supplier of high-quality research chemicals, we provide ML365 to scientists worldwide. Our commitment to excellence ensures that every batch meets stringent purity standards, guaranteeing reliable and reproducible results. Whether you are purchasing ML365 for fundamental research, exploring new therapeutic targets, or conducting in vitro assays, you can trust our product’s quality.

The ability to accurately study the effects of inhibiting TASK-1 channels is vital for advancing our understanding of conditions such as chronic pain, epilepsy, and certain cardiac arrhythmias. ML365 enables researchers to perform these targeted investigations effectively. If you are looking to buy ML365, our platform offers a straightforward purchasing process, backed by expert support.

For those in need of bulk quantities or seeking a reliable supplier for ongoing research projects, we offer competitive pricing and efficient delivery. As a manufacturer based in China, we are well-positioned to serve the global research community. We encourage you to reach out for a quote or a sample to experience the quality of our ML365 and discuss your specific research requirements.

Our mission is to support scientific advancement by providing the tools researchers need. ML365 is a testament to this commitment, offering a precise way to investigate the critical role of TASK-1 potassium channels. Partner with us for your research chemical needs and contribute to groundbreaking discoveries in the field of ion channel biology.