For R&D professionals and procurement managers in the chemical and pharmaceutical industries, understanding the market dynamics for essential building blocks is crucial. Fmoc-4-carboxymethyl-piperazine, a key reagent in peptide synthesis and drug development, is no exception. This article aims to shed light on factors influencing its price, where to source it effectively, and why its purity is paramount.

Fmoc-4-carboxymethyl-piperazine (CAS: 180576-05-0) is characterized by its white to off-white powder appearance and its high purity, typically specified as ≥98% by HPLC. This compound serves as a vital intermediate, enabling researchers to construct complex peptide chains and modify nascent drug candidates for improved pharmacological properties. Its application in areas like peptide-drug conjugates (PDCs) and targeted therapies highlights its importance in advanced pharmaceutical research.

When you are looking to buy Fmoc-4-carboxymethyl-piperazine, several factors will influence the price. These include the scale of the order (gram to kilogram quantities), the supplier's geographical location, manufacturing costs, and the level of quality control applied. Sourcing from a manufacturer in China, for instance, can often provide a competitive advantage due to optimized production processes and economies of scale. However, it is essential to vet suppliers thoroughly to ensure consistent quality and reliable delivery.

Several online chemical marketplaces and direct manufacturer websites list Fmoc-4-carboxymethyl-piperazine. When evaluating potential suppliers, pay close attention to:

  • Product Specifications: Confirm the stated purity (e.g., ≥98% HPLC) and physical appearance.
  • Certificates of Analysis (CoA): A detailed CoA is a must-have to verify batch-to-batch consistency.
  • Supplier Reputation: Look for established companies with positive reviews and a history of serving the pharmaceutical/biotech sector.
  • Lead Times: Understand the typical delivery timeframe, especially for larger orders.
  • Customer Service: Responsive communication from the sales and technical support teams is a good indicator of a reliable partner.

For organizations requiring significant quantities, requesting a bulk quotation from manufacturers directly can lead to substantial cost savings. Establishing a relationship with a trusted supplier can also ensure a more predictable supply chain, which is critical for ongoing R&D projects and manufacturing timelines.

In essence, securing high-quality Fmoc-4-carboxymethyl-piperazine at a competitive price requires a strategic approach to sourcing. By focusing on purity, understanding supplier capabilities, and leveraging market knowledge, you can effectively procure this essential chemical intermediate. We pride ourselves on being a dependable manufacturer and supplier, offering competitive pricing for your peptide synthesis and drug development needs.