In the complex world of pharmaceutical manufacturing, the precise synthesis of chiral molecules is paramount. One such indispensable compound is (R)-(+)-1-Phenylethylamine, identified by its CAS number 3886-69-9. This versatile chiral amine serves as a critical building block and a powerful tool for ensuring the enantiomeric purity of Active Pharmaceutical Ingredients (APIs). For procurement managers and R&D scientists seeking to buy this essential chemical, understanding its applications and sourcing reliably is key.

What is (R)-(+)-1-Phenylethylamine?

Also known as (R)-(+)-alpha-methylbenzylamine, this primary amine is characterized by its chiral center, meaning it exists in two non-superimposable mirror-image forms, or enantiomers. The 'R' designation signifies its specific spatial arrangement, which is crucial for its function in stereoselective synthesis. Its molecular formula is C8H11N, and it typically appears as a clear, colorless liquid with a high assay, often exceeding 99.0%.

Key Applications in Pharmaceutical Synthesis and Research

The primary utility of (R)-(+)-1-Phenylethylamine lies in two main areas:

  1. Chiral Resolution: This compound acts as a chiral resolving agent. By forming diastereomeric salts with racemic mixtures of chiral acids, it allows for the separation of these enantiomers. This process is fundamental in obtaining enantiomerically pure drugs, which often exhibit distinct pharmacological activities and safety profiles compared to their racemates.
  2. Chiral Auxiliary/Building Block: It is frequently employed as a chiral auxiliary or building block in the synthesis of various pharmaceutical intermediates and APIs. Its inherent chirality can direct subsequent reactions, leading to the formation of desired stereoisomers with high enantiomeric excess. For instance, it plays a role in the synthesis of drugs like Pregabalin.

Why Source from a Reputable Manufacturer?

Given its critical role in pharmaceutical applications, the purity and consistent quality of (R)-(+)-1-Phenylethylamine are non-negotiable. For companies looking to buy this chemical, partnering with a trusted manufacturer and supplier is essential. A reliable supplier, such as NINGBO INNO PHARMCHEM CO.,LTD., ensures that the product meets stringent quality standards, offering certifications like SGS and providing comprehensive documentation such as Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS). This diligence guarantees that your production processes are not compromised by off-spec materials.

Procurement Considerations: Price and Availability

When considering the purchase of (R)-(+)-1-Phenylethylamine, factors like price and availability are significant. By sourcing directly from established manufacturers in China, you can often secure competitive pricing while maintaining high-quality assurance. Companies like NINGBO INNO PHARMCHEM CO.,LTD. facilitate easier procurement through online support and readily available stock, catering to both research quantities and bulk industrial orders.

In conclusion, (R)-(+)-1-Phenylethylamine is a cornerstone chemical for any organization involved in chiral drug development and synthesis. Understanding its applications and ensuring a reliable supply chain from a reputable manufacturer will significantly contribute to the success of your projects. We encourage you to reach out for a quote or more information on how to buy this vital intermediate.