For procurement managers in the life sciences and pharmaceutical sectors, sourcing high-quality research chemicals is paramount. Today, we focus on NSC-87877, a critical compound for understanding cellular signaling pathways, particularly those involving protein tyrosine phosphatases (PTPs) like SHP2 and SHP1. As a leading supplier and manufacturer of research-grade chemicals, we aim to provide insights into why NSC-87877 is a valuable addition to your procurement list and how you can benefit from our direct sourcing capabilities from China.

What is NSC-87877 and Why is it Important?

NSC-87877, identified by CAS number 56990-57-9, is a well-characterized small molecule that acts as a potent inhibitor for SHP2 and SHP1 protein tyrosine phosphatases. These enzymes play crucial roles in various cellular processes, including cell growth, differentiation, and immune response. Dysregulation of PTP activity is frequently implicated in diseases such as cancer, making inhibitors like NSC-87877 invaluable tools for researchers investigating these complex mechanisms. Its known biological activity includes inhibiting EGF-induced Erk1/2 activation and reducing cell viability in certain cancer cell lines, highlighting its potential in cancer research and drug discovery.

Key Applications in Research:

  • Cancer Biology: NSC-87877 has shown promise in research related to neuroblastoma, demonstrating anti-proliferative and pro-apoptotic effects. For research institutions and pharmaceutical companies, purchasing this compound allows for in-depth studies into targeted cancer therapies.
  • Signal Transduction Pathways: Researchers utilize NSC-87877 to dissect the intricate roles of SHP2 and SHP1 in various signaling cascades, contributing to a deeper understanding of cellular communication and disease pathogenesis.
  • Enzyme Inhibition Studies: As a potent PTP inhibitor, NSC-87877 is essential for in vitro assays aimed at understanding enzyme kinetics, screening for new therapeutic targets, and validating biological hypotheses.

Procurement Advantages: Sourcing from China

When considering your procurement strategy for research chemicals like NSC-87877, partnering with a reputable manufacturer and supplier based in China offers significant advantages. These include:

  • Cost-Effectiveness: Direct sourcing often translates to more competitive pricing compared to distributors, allowing your research budget to stretch further.
  • Reliable Supply: Established manufacturers maintain consistent production, ensuring a stable supply chain to meet your ongoing research demands.
  • Quality Assurance: Reputable suppliers adhere to strict quality control measures, guaranteeing the purity (often ≥98% by HPLC) and potency of the chemicals you buy.

How to Buy NSC-87877: Your Next Steps

For procurement managers seeking to buy NSC-87877 or other high-quality research chemicals, engaging directly with manufacturers can streamline the process. We, as a dedicated supplier and manufacturer from China, are committed to providing researchers with reliable access to essential compounds. We encourage you to request a quote for your specific needs, inquire about bulk purchase options, and explore our comprehensive product catalog. Our aim is to be your trusted partner in advancing scientific discovery.

By understanding the importance of NSC-87877 and leveraging the benefits of direct sourcing from China, procurement professionals can effectively equip their research teams with the high-quality tools they need to succeed.