In the pursuit of scientific advancement, researchers constantly seek reliable and potent chemical tools to investigate complex biological pathways. NSC-87877, a well-established inhibitor of protein tyrosine phosphatases (PTPs) SHP2 and SHP1, is one such indispensable compound. This article aims to shed light on its importance, applications in research, and the advantages of procuring it from a trusted supplier, emphasizing the value proposition for scientists and procurement specialists alike.

Understanding the Significance of NSC-87877

NSC-87877, identified by its CAS number 56990-57-9, is lauded for its robust inhibitory action against SHP2 and SHP1. These enzymes are key regulators of numerous cellular processes, and their dysregulation is associated with a spectrum of diseases, particularly cancers. The compound's biological activity, characterized by potent IC50 values against various PTPs and its documented effects on cancer cell proliferation, makes it a prime candidate for laboratory investigations. Its utility is further underscored by its role in modulating key signaling pathways, offering researchers a precise tool to study enzyme function and its impact on cellular outcomes.

Applications in Scientific Research:

  • Signal Transduction Investigation: NSC-87877 allows researchers to precisely modulate SHP2 and SHP1 activity, facilitating the exploration of their roles in various signaling cascades that govern cell growth, survival, and differentiation.
  • Pre-clinical Cancer Studies: Its demonstrated activity in inhibiting neuroblastoma cell proliferation and inducing apoptosis makes it an invaluable reagent for laboratories working on novel cancer therapies. Acquiring this compound is a direct step towards advancing these critical research areas.
  • Biochemical Assays: The high purity (≥98% by HPLC) of NSC-87877, coupled with its potent inhibitory effects, makes it ideal for kinetic studies and screening programs focused on PTPs.

The Advantage of Direct Sourcing

For research institutions and companies, securing a consistent and high-quality supply of chemicals like NSC-87877 is essential. Partnering with a direct manufacturer and supplier, particularly those based in China, presents several key benefits:

  • Cost Efficiency: Direct sourcing often leads to more competitive pricing, maximizing research budgets.
  • Assured Quality: Reputable manufacturers adhere to stringent quality control standards, ensuring the reliability and purity of the compounds.
  • Supply Chain Stability: A direct relationship provides greater assurance of timely delivery and continuous availability for ongoing research projects.

How to Acquire NSC-87877 for Your Research

We are dedicated to empowering scientific discovery by providing researchers with access to premium quality chemicals. If your work involves PTP inhibition, signal transduction, or cancer research, NSC-87877 is a compound you should consider. We invite you to request a quotation, inquire about bulk orders, and explore our comprehensive range of research chemicals. Our commitment is to be your trusted partner, ensuring you have the necessary tools to achieve your research objectives.