Intermediates

2-[1-(Mercaptomethyl)Cyclopropyl]Acetic Acid

  • CAS No.162515-68-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2-[1-(Mercaptomethyl)Cyclopropyl]Acetic Acid designed for pharmaceutical synthesis. Reliable bulk supply with comprehensive COA and global shipping capabilities.

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Product Technical Details

Product Overview

2-[1-(Mercaptomethyl)Cyclopropyl]Acetic Acid represents a critical building block in the synthesis of advanced pharmaceutical compounds. This specialized organic intermediate is characterized by its unique cyclopropyl structure combined with a mercaptomethyl functional group, offering high reactivity and stability for complex coupling reactions. Our manufacturing process ensures consistent quality suitable for large scale production environments where precision and purity are paramount.

As a key precursor in the production of leukotriene receptor antagonists, this compound plays an vital role in the respiratory therapeutic sector. We maintain strict control over every batch to guarantee that the chemical integrity meets the rigorous demands of modern drug development pipelines. Our facility is equipped to handle sensitive thiol containing compounds with appropriate inert gas protection to prevent oxidation during storage and transit.

Physical and Chemical Properties

The compound exhibits distinct physical characteristics that facilitate its handling in industrial settings. With a molecular formula of C6H10O2S and a molecular weight of 146.21 g/mol, it presents as a white to off-white crystalline powder. The melting point ranges between 42 to 45 degrees Celsius, indicating stable solid state properties at ambient temperatures. The density is approximately 1.2 g/cm3, and the boiling point is recorded at 290.1 degrees Celsius under standard atmospheric pressure. These properties ensure manageable processing conditions during downstream synthesis steps.

Quality Specifications and Analysis

Quality assurance is the cornerstone of our manufacturing philosophy. Each batch undergoes comprehensive testing using gas chromatography, high performance liquid chromatography, and inductively coupled plasma spectroscopy. We monitor residual solvents, heavy metal content, and specific impurities to ensure compliance with international pharmaceutical standards. The assay value consistently exceeds 99 percent, minimizing the need for extensive purification by our clients.

ParameterSpecificationTypical Result
AppearanceWhite to off-white powderOff-white powder
Assay by GC98.0 Percent Min99.0 Percent
Chromatographic Purity98.0 Percent Min99.3 Percent
Loss on Drying0.5 Percent Max0.3 Percent
Residual SolventsCompliant with ICH GuidelinesConform
Lithium Content10 ppm MaxConform

Industrial Applications

This intermediate is primarily utilized in the synthesis of Montelukast, a widely prescribed medication for asthma and allergy management. The high purity profile of our product ensures efficient reaction kinetics and reduces the formation of side products during the coupling stages. Pharmaceutical manufacturers rely on our consistent supply chain to maintain their production schedules without interruption. We support custom synthesis requests and can adjust packaging specifications to align with specific process requirements.

Packaging and Storage

To maintain stability, the product is packaged in 25 kilogram cardboard drums or according to customer specified requirements. Storage recommendations include keeping the container tightly closed in a cool and dry environment. Inert gas protection is advised to prevent degradation of the thiol group. We ensure all shipments are protected from moisture and strong light or heat sources during logistics. Our global distribution network guarantees timely delivery with full documentation including certificates of analysis and safety data sheets.