1-Chloro-4-fluoro-2-nitrobenzene
- CAS No.345-17-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 1-Chloro-4-fluoro-2-nitrobenzene (CAS 345-17-5) serving as a critical fluorinated building block for advanced pharmaceutical and agrochemical synthesis processes.
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Product Overview
1-Chloro-4-fluoro-2-nitrobenzene represents a vital component in the realm of advanced organic synthesis, specifically within the domain of fluorinated aromatic compounds. As a specialized chemical intermediate, this substance serves as a foundational building block for the development of complex pharmaceutical agents and agrochemical formulations. Our facility ensures that every batch meets rigorous international standards, providing reliability for downstream manufacturing processes.
The unique structural configuration, featuring both chloro and fluoro substituents on the nitrobenzene ring, enables versatile reactivity profiles. This makes it an indispensable reagent for chemists engaged in nucleophilic aromatic substitution reactions. We prioritize consistency and purity to support high-yield synthesis routes.
Technical Specifications
| CAS Number | 345-17-5 |
|---|---|
| Molecular Formula | C6H3ClFNO2 |
| Molecular Weight | 175.55 g/mol |
| Purity | ≥98.0% |
| Appearance | Light yellow crystalline powder |
| Melting Point | 37-40 °C |
| Boiling Point | 238 °C |
| Density | 1.494 g/cm3 |
Industrial Applications
This fluorinated intermediate is extensively utilized in the production of high-value fine chemicals. Its primary application lies in the pharmaceutical industry, where it acts as a precursor for various therapeutic compounds requiring specific halogenated motifs. The introduction of fluorine atoms often enhances metabolic stability and bioavailability in drug candidates. Additionally, it finds utility in agrochemical synthesis, contributing to the creation of advanced crop protection agents.
- Pharmaceutical API synthesis and drug discovery programs.
- Agrochemical intermediate for pesticide and herbicide development.
- Material science applications requiring fluorinated aromatic structures.
- Custom organic synthesis projects requiring high-purity starting materials.
Chemical Properties and Reactivity
Regarding chemical stability and reactivity, this compound exhibits characteristic behavior of activated aryl halides. The presence of the nitro group ortho to the chloro substituent activates the ring towards nucleophilic attack, facilitating substitution reactions under controlled conditions. The fluoro substituent provides additional opportunities for selective functionalization. Users should handle this material with appropriate personal protective equipment due to its chemical nature.
Quality Assurance and Handling
We maintain a robust quality management system to guarantee the integrity of 1-Chloro-4-fluoro-2-nitrobenzene. Each production lot undergoes comprehensive analytical testing, including HPLC and GC analysis, to verify purity levels and impurity profiles. A Certificate of Analysis (COA) is provided with every shipment to ensure full transparency and compliance with your internal quality protocols.
Proper storage is essential to maintain chemical stability. The product should be kept in tightly sealed containers within a cool, dry, and well-ventilated environment. It must be stored away from incompatible substances such as strong oxidizing agents and bases. Our packaging options include 25kg drums, designed to protect the material during global transit while ensuring safety and ease of handling. Partner with us for a reliable supply chain of critical chemical intermediates. Our team is dedicated to supporting your research and production needs with timely delivery and competitive bulk pricing structures.
