2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one

Product Overview

We are pleased to offer premium grade 2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one, a critical spirocyclic intermediate identified by CAS number 138402-05-8. This specialized chemical compound serves as a foundational building block in the pharmaceutical industry, specifically utilized in the multi-step synthesis of antihypertensive agents. Our manufacturing facility adheres to rigorous quality assurance protocols to ensure that every batch meets the highest standards of purity and consistency required for downstream drug production.

As a dedicated supplier of advanced organic synthesis materials, we understand the importance of supply chain reliability. This product is synthesized using optimized reaction pathways that maximize yield while minimizing impurities. The resulting material is characterized by its distinct physical properties, appearing as a brown oil with a high assay value suitable for sensitive pharmaceutical applications. Our commitment to excellence ensures that clients receive materials that facilitate efficient production schedules and regulatory compliance.

Technical Specifications

The following table outlines the key physical and chemical properties of this intermediate. These parameters are verified through advanced analytical techniques including HPLC and NMR spectroscopy to guarantee accuracy.

Industrial Applications

The primary application of 2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one is in the manufacture of Irbesartan, a widely prescribed angiotensin II receptor antagonist used to treat high blood pressure and diabetic nephropathy. The spirocyclic structure of this intermediate is essential for establishing the correct stereochemistry and pharmacophore alignment in the final active pharmaceutical ingredient. High purity levels are crucial at this stage to prevent the formation of unwanted byproducts that could complicate purification processes later in the synthesis route.

Beyond its specific role in Irbesartan production, this diazaspiro compound represents a valuable scaffold for medicinal chemistry research. Researchers exploring novel cardiovascular therapeutics may utilize this building block to develop analogs with improved pharmacokinetic profiles. Our team supports both large-scale commercial manufacturing and smaller-scale research requirements, providing flexibility in packaging and delivery to meet diverse project needs.

Quality Assurance and Logistics

Quality control is paramount in our operations. Each production batch undergoes comprehensive testing, and a Certificate of Analysis (COA) is provided with every shipment. This documentation verifies that the product conforms to all specified parameters, including identity, purity, and physical characteristics. We maintain strict storage conditions, recommending that the material be kept in a cool, ventilated environment to preserve stability and prevent degradation over time.

We offer flexible packaging options to suit your operational requirements, including standard 200 kg drums or custom configurations based on client specifications. Our global logistics network ensures timely delivery to laboratories and manufacturing plants worldwide. By choosing our company as your partner, you gain access to a reliable source of high-quality pharmaceutical intermediates backed by decades of industry experience and a commitment to customer satisfaction. Contact our sales team today for detailed pricing information and technical support.