Intermediates

2,6-Diamino-9-(β-D-arabinofuranosyl)purine

  • CAS No.34079-68-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,6-Diamino-9-(β-D-arabinofuranosyl)purine (CAS 34079-68-0), a key nucleoside intermediate for advanced pharmaceutical synthesis.

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Product Technical Details

Product Overview

2,6-Diamino-9-(β-D-arabinofuranosyl)purine is a specialized purine nucleoside derivative widely employed as a critical building block in the synthesis of complex pharmaceutical active ingredients. With a molecular formula of C₁₀H₁₄N₆O₄ and a molecular weight of 282.26 g/mol, this compound features a β-D-arabinofuranosyl sugar moiety linked to the 9-position of a 2,6-diaminopurine base, offering unique reactivity and selectivity in medicinal chemistry applications.

Specifications

Molecular FormulaC₁₀H₁₄N₆O₄
Molecular Weight282.256 g/mol
Density2.25 g/cm³
Boiling Point798.5°C
Flash Point436.7°C
AppearanceWhite or off-white crystalline powder
Assay (HPLC)≥98.0%
Loss on Drying≤1.0%

Industrial Applications

This high-purity nucleoside serves primarily as an intermediate in the development and large-scale manufacturing of antiviral and anticancer therapeutics. Its structural motif enables strategic incorporation into modified oligonucleotides or small-molecule APIs targeting specific enzymatic pathways. Due to its defined stereochemistry and functional group compatibility, it is particularly valued in research programs focused on nucleotide analogs and advanced organic synthesis.

  • Ideal for use in multi-step pharmaceutical synthesis requiring stringent quality control
  • Compatible with standard glycosylation and protection/deprotection protocols
  • Supplied with comprehensive analytical documentation including COA and HPLC chromatograms

Stored in a cool, well-ventilated environment and typically packaged in 25 kg drums (custom packaging available upon request), this intermediate meets global regulatory standards for chemical stability and batch-to-batch consistency.