4-(4-Chlorophenyl)Cyclohexanecarboxylic Acid

Product Overview

4-(4-Chlorophenyl)Cyclohexanecarboxylic Acid (CAS 49708-81-8) is a specialized organic compound serving as a critical building block in the pharmaceutical industry. This high-value intermediate is primarily utilized in the synthesis of Atovaquone, a vital antimalarial and antipneumocystis medication. Our manufacturing process ensures exceptional stereochemical control, specifically maximizing the trans-isomer content while minimizing cis-isomer impurities to meet rigorous global pharmacopeia standards.

As a dedicated chemical manufacturer, we understand the importance of consistency in API production. This carboxylic acid derivative offers excellent stability and reactivity, making it an ideal candidate for complex organic synthesis routes. The compound is characterized by its distinct crystalline structure and high melting point, which facilitates efficient purification and handling during downstream processing.

Technical Specifications

Industrial Applications

The primary application of 4-(4-Chlorophenyl)Cyclohexanecarboxylic Acid lies in the pharmaceutical sector, specifically as a key precursor for Atovaquone. The quality of this intermediate directly impacts the efficacy and safety profile of the final active pharmaceutical ingredient. Our product is engineered to support large-scale API manufacturing, ensuring that synthesis routes remain efficient and cost-effective without compromising on purity.

Beyond its primary use, this compound serves as a valuable reference standard in analytical chemistry and quality control laboratories. Its well-defined physical properties, including density and refractive index, allow for precise calibration and verification of analytical instruments used in drug development pipelines.

Quality Assurance and Storage

We implement a multi-stage quality control protocol to guarantee product integrity. Each batch undergoes comprehensive testing for identity, assay, related substances, and residual solvents. Our facility adheres to strict safety and environmental regulations, ensuring that all residual solvents such as chlorobenzene, ethanol, and toluene are maintained at non-detectable or trace levels well below regulatory limits.

To maintain stability, the product should be stored in a cool, dry, and well-ventilated area. Containers must remain tightly closed to protect against moisture and strong light. We offer flexible packing options, typically 25kg cardboard drums, customized to meet specific logistical requirements. Global shipping is available with full documentation, including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and method validation reports.