Intermediates

4-(3-Methylphenyl)Amino-3-Pyridinesulfonamide

  • CAS No.72811-73-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity pharmaceutical intermediate used primarily in the synthesis of Torasemide. Available in bulk quantities with comprehensive quality documentation.

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Product Technical Details

Product Overview

4-(3-Methylphenyl)Amino-3-Pyridinesulfonamide is a critical organic compound utilized extensively within the pharmaceutical industry. This specialized chemical serves as a key building block in the multi-step synthesis of advanced diuretic medications. Our facility produces this intermediate under strict quality control protocols to ensure consistency and reliability for downstream manufacturing processes. The compound is characterized by its stable chemical structure and high reactivity profile, making it an ideal candidate for complex organic synthesis routes.

As a dedicated manufacturer, we understand the importance of supply chain stability for pharmaceutical producers. We offer this material with full traceability and supporting documentation to facilitate regulatory compliance in your final drug product filings. Our production capabilities allow us to meet both pilot-scale and commercial-scale demands efficiently.

Technical Specifications

The following table outlines the key physical and chemical properties verified through our internal quality assurance laboratories. Each batch is tested against these parameters before release to ensure it meets the stringent requirements of pharmaceutical applications.

ParameterSpecification
CAS Number72811-73-5
Molecular FormulaC12H13N3O2S
Molecular Weight263.32 g/mol
AppearanceWhite to off-white crystalline powder
Purity≥99.0%
Melting Point162-164°C
Loss on Drying≤0.5%
Residue on Ignition≤0.2%
Individual Impurity≤0.3%

Industrial Applications

This sulfonamide derivative is primarily employed as an intermediate in the manufacture of Torasemide, a potent loop diuretic used to treat fluid retention and high blood pressure. The high purity level of our product ensures minimal byproduct formation during subsequent coupling reactions, thereby improving overall yield and reducing purification costs for our clients. Beyond this primary application, the chemical structure offers versatility for research and development into novel sulfonamide-based therapeutics.

Our technical team supports customers with detailed synthesis route information and safety data to optimize process efficiency. We recognize that consistency in raw material quality is paramount for maintaining the efficacy and safety profile of the final pharmaceutical product.

Quality Assurance and Storage

Quality is the cornerstone of our manufacturing philosophy. Every production batch undergoes rigorous testing using high-performance liquid chromatography and other analytical methods to verify identity and purity. We provide a Certificate of Analysis with every shipment, detailing all test results against specified limits. Our facility adheres to good manufacturing practices to minimize contamination risks.

For optimal stability, the product should be stored in a tightly closed container within a cool, dry, and well-ventilated area. It is essential to keep the material away from incompatible substances such as strong oxidizing agents. Proper handling procedures should be followed to maintain integrity during transport and storage. We offer flexible packing options, including 25kg cardboard drums, customized to meet specific logistical requirements.