4'-Chloro-2',5'-Dimethoxyacetoacetanilide Bulk Price Global Manufacturer 2026
- Technical Grade: CAS 4433-79-8 with melting point 102-104°C and high industrial purity for pigment synthesis.
- Procurement: Bulk pricing structures available for 25kg drums and metric ton quantities from verified facilities.
- Supply Chain: Reliable global manufacturer ensuring consistent COA documentation and stable logistics for 2026.
In the specialized sector of organic pigment intermediates, 4'-Chloro-2',5'-dimethoxyacetoacetanilide stands as a critical coupling component for producing high-performance azoic pigments. Known chemically as N-(4-chloro-2,5-dimethoxyphenyl)-3-oxo-Butanamide, this compound is essential for manufacturers seeking vibrant yellow to orange hues in industrial applications. As we approach 2026, the demand for consistent quality and competitive bulk pricing has intensified. NINGBO INNO PHARMCHEM CO.,LTD. positions itself as the premier global manufacturer capable of meeting these rigorous technical and commercial requirements.
Understanding the market dynamics for CAS 4433-79-8 requires a deep dive into both the chemical synthesis parameters and the commercial grading scales. Laboratory-scale pricing often skews significantly higher due to packaging and handling overheads, whereas industrial procurement focuses on reaction yields and purity consistency. This analysis provides a comprehensive overview of the technical specifications, synthesis routes, and bulk price trends necessary for strategic sourcing.
Technical Specifications and Chemical Properties
For process chemists and procurement officers, verifying the physical constants of the material is the first step in quality assurance. The compound, occasionally referenced in legacy literature as Naphtol As-lgll, exhibits specific thermal and structural properties that dictate its handling and storage. The molecular formula C12H14ClNO4 and a molecular weight of 271.7 g/mol define its stoichiometry in coupling reactions.
The following table outlines the critical physical properties required for technical validation:
| Property | Specification |
|---|---|
| CAS Number | 4433-79-8 |
| Molecular Formula | C12H14ClNO4 |
| Molecular Weight | 271.7 g/mol |
| Melting Point | 102-104°C |
| Appearance | White to Light Yellow Powder |
| Density | 1.277 g/cm³ |
| Storage Conditions | Sealed in dry, Room Temperature |
Maintaining the integrity of these properties during transport is vital. The vapor pressure is negligible (0-0.001Pa at 20-50℃), indicating low volatility, but the material must be protected from moisture to prevent hydrolysis of the acetoacetyl group. Industrial purity standards typically require assay values exceeding 98.0% (HPLC) to ensure predictable color strength and shade in the final pigment.
Synthesis Route and Manufacturing Process
The production of this intermediate involves the acetoacetylation of 4-chloro-2,5-dimethoxyaniline. The efficiency of this synthesis route directly impacts the bulk price and availability of the final product. Key process parameters include the control of reaction temperature, the stoichiometric ratio of diketene or ethyl acetoacetate, and the purification method employed post-reaction.
High-quality manufacturing facilities utilize recrystallization techniques to remove unreacted aniline and side products. This step is crucial for achieving the necessary industrial purity required by downstream pigment formulators. Impurities can lead to off-shades or reduced lightfastness in the final application. When sourcing high-purity Azoic Coupling Component 44, buyers should prioritize suppliers who demonstrate strict control over these crystallization parameters.
Scale-up from kilogram to metric ton quantities often introduces challenges in heat dissipation and mixing efficiency. A robust global manufacturer will have engineered reactors capable of maintaining uniform conditions throughout the batch, ensuring that the material supplied in 2026 matches the quality of previous lots. Consistency in the melting point range (102-104°C) is a primary indicator of successful process control.
Global Supply Chain and Bulk Pricing Trends
Market analysis indicates significant variance in pricing based on quantity and packaging. Small-scale research quantities (25g to 100g) often command premiums ranging significantly higher per kilogram compared to industrial drum shipments. Data suggests that while laboratory packs may cost upwards of $30 to $446 depending on the vendor and package size, bulk industrial procurement operates on a different economic model.
For B2B transactions, pricing is typically structured around 25kg fiber drums or bulk bags. The cost per kilogram decreases substantially as volume increases, reflecting the efficiencies of large-scale production and logistics. In the 2026 market landscape, stability in raw material costs for chlorinated anilines and acetoacetylating agents will influence the final bulk price. Procurement teams should anticipate contracts that lock in rates for quarterly or annual volumes to mitigate market volatility.
Comparing Lab Scale vs Industrial Drum Costs
Understanding the cost disparity between research-grade and production-grade material is essential for budgeting. The table below illustrates the typical market structure observed across different packaging tiers:
| Packaging Tier | Typical Volume | Price Influence | Primary Use Case |
|---|---|---|---|
| Laboratory | 25g - 100g | High Premium | R&D, Small Batch Testing |
| Pilot Scale | 500g - 5kg | Moderate | Process Optimization |
| Industrial | 25kg - 1000kg | Competitive Bulk Rate | Commercial Pigment Production |
It is evident that relying on laboratory suppliers for production needs is economically unfeasible. Engaging directly with a manufacturing source like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to industrial pricing tiers that align with commercial manufacturing budgets.
Requesting Quotes for 25 kg Drum Shipments
Securing a reliable supply chain for 2026 requires proactive engagement with manufacturers. When requesting a quote for 25 kg drum shipments, buyers should specify their purity requirements and intended application. This allows the supplier to recommend the appropriate grade, whether it be standard technical grade or a highly purified variant for sensitive applications.
Documentation is a critical component of the procurement process. A complete COA (Certificate of Analysis) should accompany every shipment, detailing the assay, melting point, and loss on drying. If a COA is not immediately available online, reputable suppliers have streamlined processes to generate these documents upon request. Buyers should ensure that the batch number on the COA matches the physical labeling on the drums to maintain traceability.
Furthermore, logistics play a pivotal role in total landed cost. A true global partner will offer flexible Incoterms, such as FOB or CIF, to suit the buyer's import capabilities. Lead times should be clearly defined, with production slots booked in advance to accommodate large volume requirements. By establishing a direct line of communication with the manufacturing team, clients can navigate potential supply chain disruptions and ensure uninterrupted production flows.
Conclusion
The market for 4'-Chloro-2',5'-dimethoxyacetoacetanilide is evolving towards higher efficiency and transparency. For pigment manufacturers, the choice of supplier directly impacts product quality and bottom-line profitability. By prioritizing industrial purity, verified synthesis routes, and transparent bulk pricing, companies can secure a competitive advantage in the 2026 marketplace. NINGBO INNO PHARMCHEM CO.,LTD. remains committed to delivering these technical advantages through robust manufacturing capabilities and dedicated customer support.