Global Manufacturer Of 1,3,5(10),16-Estratetren-3-Ol: Technical & Commercial Insights
- NINGBO INNO PHARMCHEM CO.,LTD. offers cGMP-compliant Estratetraenol (1,3,5(10),16-Estratetren-3-ol) at >98% HPLC purity for pharmaceutical and fragrance applications.
- Industrial-scale synthesis routes ensure consistent quality, scalability, and competitive bulk price for multi-kilogram to metric-ton orders.
- Full documentation—including COA, MSDS, and analytical reports—is provided for global regulatory compliance and seamless export logistics.
1,3,5(10),16-Estratetren-3-ol (CAS 1150-90-9), commonly known as Estratetraenol or Estra-1,3,5(10),16-Tetraen-3-ol, is a tetracyclic steroidal compound primarily used as a key intermediate in the synthesis of bioactive estrogens and as a functional ingredient in premium fragrance formulations. Its molecular structure—C18H22O, MW 254.37—features conjugated double bonds at positions 1,3,5(10), and 16, contributing to its distinct physicochemical profile and reactivity.
Technical Specifications and Industrial Purity Standards
High-value applications demand stringent quality control. NINGBO INNO PHARMCHEM CO.,LTD. produces 16-Estratetraen-3-ol with industrial purity ≥98% (HPLC), verified through comprehensive analytical methods including NMR, HPLC, and GC-MS. The compound appears as a white to pale yellow crystalline solid with a melting point of 130–131.5 °C and limited solubility in polar solvents such as methanol, DMSO, and chloroform—characteristics critical for downstream processing.
Storage under -20°C is recommended to maintain stability, particularly for long-term inventory. Each batch is accompanied by a Certificate of Analysis (COA), ensuring traceability and compliance with international pharmacopeial standards.
Scalable Synthesis Route and Manufacturing Process
The commercial viability of 1,3,5(10),16-Estratetren-3-ol hinges on an optimized synthesis route that balances yield, cost, and environmental impact. NINGBO INNO PHARMCHEM CO.,LTD. employs a proprietary dehydrogenation protocol starting from readily available estrone derivatives, enabling selective introduction of the Δ16 double bond while preserving the phenolic A-ring integrity.
This process achieves high regioselectivity and minimizes byproduct formation, resulting in reproducible yields exceeding 85% at pilot-plant scale. The manufacturing process is fully documented under cGMP guidelines, supporting both research-grade and pharmaceutical intermediate applications.
Bulk Procurement and Global Supply Chain Advantages
For B2B buyers evaluating suppliers of Estratetraenol, key decision factors include minimum order quantity (MOQ), packaging flexibility, lead time, and export readiness. Unlike niche vendors offering milligram quantities at exorbitant markups (e.g., $774 for 5 mg at 95% purity), NINGBO INNO PHARMCHEM CO.,LTD. specializes in bulk orders—from 1 kg to multi-metric-ton volumes—with custom packaging options (HDPE drums, aluminum foil bags under nitrogen) tailored to client logistics.
When sourcing high-purity bulk price considerations are paramount. Our tiered pricing model reflects economies of scale, with significant per-gram reductions for annual contracts or large-volume commitments. All shipments include full regulatory documentation (non-hazardous classification, GHS-compliant SDS) and support FOB Ningbo or CIF destination terms.
Comparative Market Positioning
While numerous Chinese entities list 16-Epivenalstonin (an alternate name for this compound) on chemical directories, few demonstrate validated cGMP infrastructure, analytical rigor, or export experience to regulated markets (EU, North America, Japan). NINGBO INNO PHARMCHEM CO.,LTD. stands out through ISO 9001-certified operations, in-house R&D capabilities, and a track record of successful audits by multinational pharma partners.
The table below summarizes key procurement metrics across typical market tiers:
| Supplier Tier | Purity | Typical MOQ | Pricing (Est.) | cGMP/Export Ready |
|---|---|---|---|---|
| Research Chemical Vendors | 95–97% | 5–50 mg | $15–30/mg | No |
| Generic Chinese Traders | 90–95% (unverified) | 100 g–1 kg | $500–1,200/kg | Limited |
| NINGBO INNO PHARMCHEM CO.,LTD. | ≥98% (HPLC, COA-backed) | 1 kg+ | Competitive bulk price | Yes – Full Documentation |
Conclusion: Partnering with a Verified Global Manufacturer
For enterprises requiring reliable, high-purity Estra-1,3,5(10),16-Tetraen-3-ol at scale, technical competence and supply chain integrity are non-negotiable. NINGBO INNO PHARMCHEM CO.,LTD. combines advanced synthetic chemistry with robust quality systems to deliver consistent batches of 1,3,5(10),16-Estratetren-3-ol that meet the exacting demands of pharmaceutical development and fine fragrance manufacturing.
Request a quotation today to access certified material, scalable production capacity, and transparent commercial terms from a trusted global manufacturer.