Intermediates

Estratetraenol

  • CAS No.1150-90-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Estratetraenol (CAS 1150-90-9) is a key steroid intermediate widely used in advanced pharmaceutical synthesis.

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Product Technical Details

Product Overview

Estratetraenol (CAS 1150-90-9) is a high-value steroidal compound classified as a tetracyclic unsaturated alcohol. With its distinctive conjugated diene structure and hydroxyl functionality at the C3 position, it serves as a critical building block in the synthesis of complex pharmaceutical active ingredients. This compound is rigorously manufactured under cGMP-compliant conditions to ensure consistent quality and batch-to-batch reproducibility for demanding medicinal chemistry applications.

Specifications

Molecular FormulaC₁₈H₂₂O
Molecular Weight254.37 g/mol
Exact Mass254.16700
Density1.111 g/cm³
Boiling Point400.2°C at 760 mmHg
Flash Point180.6°C
LogP4.41440
PSA20.23 Ų
Vapor Pressure5.59 × 10⁻⁷ mmHg at 25°C
Refractive Index1.592
AppearanceWhite powder
Assay≥99.0%

Industrial Applications

Estratetraenol is primarily employed as a specialized intermediate in the multi-step synthesis of steroidal therapeutics. Its unique estra-1,3,5(10),16-tetraene scaffold enables strategic functionalization for the development of novel hormonal modulators and anti-inflammatory agents. Due to its structural complexity and defined stereochemistry, it is particularly valuable in research programs targeting nuclear receptor ligands and endocrine pathway regulators.

  • Serves as a core scaffold for advanced organic synthesis in drug discovery
  • Enables efficient construction of modified estrogenic frameworks
  • Compatible with modern catalytic and protecting-group strategies
  • Supplied with full analytical documentation including COA and spectral data

For optimal stability, store Estratetraenol in a tightly sealed container in a cool, dry, and well-ventilated area away from direct light and oxidizing agents. Standard packaging is 25 kg per drum, with custom configurations available upon request to meet specific logistical or regulatory requirements.