6,7-Dimethoxy-3H-Quinazolin-4-One Bulk Price 2026: Market Forecast & Procurement Guide
- For R&D: Validated synthesis routes ensuring ≥98.0% HPLC purity and consistent melting point profiles (298°C).
- For Procurement: Access tonnage quantities with transparent bulk price structures and factory-direct lead times.
- For Executives: Mitigate supply chain risk with regulatory compliance and scalable manufacturing capacity.
As the pharmaceutical landscape shifts toward targeted kinase inhibitors, the demand for key heterocyclic intermediates continues to rise. Specifically, the market for 6,7-Dimethoxy-3H-quinazolin-4-one is evolving, driven by its critical role as a gefitinib precursor and scaffold for novel oncology therapeutics. Procurement managers and technical directors must navigate fluctuating raw material costs and logistics constraints to secure stable supply lines for 2026 and beyond.
At NINGBO INNO PHARMCHEM CO.,LTD., we understand that securing a reliable supply of this quinazoline derivative requires more than just a competitive quote; it demands a partner capable of delivering batch-to-batch consistency and rigorous quality assurance. This analysis breaks down the technical specifications, pricing forecasts, and logistical considerations essential for strategic sourcing.
2026 Bulk Price Forecast vs Retail Rates
The pricing dynamics for fine chemical intermediates are heavily influenced by upstream feedstock availability and energy costs associated with the manufacturing process. While retail rates for gram-scale quantities remain static due to packaging and handling overheads, bulk procurement strategies offer significant cost advantages. Market projections for 2026 indicate a stabilization in prices for process-scale quantities, provided buyers lock in contracts with established manufacturers.
Retail pricing often obscures the true cost of goods when scaled to production levels. By engaging directly with a global manufacturer, organizations can bypass distributor markups. The key value driver here is not merely the unit cost, but the reduction in failed batches due to impurity profiles. When sourcing high-purity 6,7-Dimethoxy-3,4-dihydroquinazoline-4-one, buyers should prioritize vendors who demonstrate control over side-reactions during cyclization, ensuring the final industrial purity meets stringent pharmacopeial standards.
Technical Specifications and Quality Parameters
For process chemists, the physical and chemical properties of the material dictate its performance in downstream reactions. The following table outlines the critical quality attributes expected for commercial grade supply.
| Parameter | Specification | Test Method |
|---|---|---|
| CAS Number | 13794-72-4 | Registry |
| Chemical Name | 6,7-Dimethoxy-3H-quinazolin-4-one (also known as 6,7-Dimethoxy-4-quinazolinol) | IUPAC |
| Molecular Weight | 206.20 g/mol | Calculated |
| Purity (HPLC) | ≥98.0% | Area Normalization |
| Melting Point | 298°C | DSC / Capillary |
| Appearance | White to Yellow Crystalline Powder | Visual |
Volume Discount Structures for Tonnes
Procurement strategies for 2026 should focus on volume-based tiering. Suppliers typically offer aggressive discount structures for commitments exceeding metric tonne quantities. This approach not only lowers the cost per kilogram but also secures production slots in the manufacturing schedule, mitigating the risk of lead time extensions during peak demand periods.
Effective negotiation involves verifying the synthesis route employed by the manufacturer. Routes that utilize cost-effective starting materials without compromising yield are essential for maintaining competitive bulk price points. NINGBO INNO PHARMCHEM CO.,LTD. optimizes these pathways to ensure that cost savings are passed down to the client without sacrificing the quality assurance protocols required for GMP-adjacent environments.
Logistics for Hazardous Chemical Shipping
For executives overseeing supply chain logistics, understanding the regulatory landscape is paramount. While this compound is generally stable, international shipping requires adherence to strict documentation standards. Proper classification ensures smooth customs clearance and avoids demurrage charges that can erode margin savings.
Key logistical considerations include:
- Documentation: Ensure every shipment is accompanied by a batch-specific COA, SDS, and Certificate of Origin to satisfy import regulations.
- Packaging: Industrial quantities should be packed in moisture-proof drums or lined bags to prevent degradation during transit.
- Compliance: Verify TSCA and REACH status if shipping to North American or European facilities to prevent regulatory hold-ups.
Strategic sourcing of critical intermediates requires a partner who balances technical expertise with commercial reliability. To secure your supply chain for the upcoming fiscal year, we invite you to contact our technical sales team for a batch-specific COA, SDS, or bulk pricing quote.