Intermediates

6,7-Dimethoxy-3,4-dihydroquinazoline-4-one

  • CAS No.13794-72-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 6,7-Dimethoxy-3,4-dihydroquinazoline-4-one (CAS 13794-72-4) designed for Gefitinib synthesis. Available in bulk with full COA and quality assurance.

Request Bulk Pricing

Product Technical Details

Product Overview

6,7-Dimethoxy-3,4-dihydroquinazoline-4-one is a specialized pharmaceutical intermediate characterized by its high chemical stability and precise molecular structure. This quinazoline derivative serves as a critical building block in the synthesis of advanced therapeutic agents, particularly within the oncology sector. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for research and development teams focused on kinase inhibitor production. The compound is rigorously tested to meet international standards for pharmaceutical raw materials.

Technical Specifications

ParameterValue
CAS Number13794-72-4
Molecular FormulaC10H10N2O3
Molecular Weight206.20 g/mol
Purity≥98%
AppearanceWhite crystalline powder
Melting Point309-311°C
Moisture Content≤1%

Industrial Applications

This chemical entity is primarily utilized as a key intermediate in the manufacturing process of Gefitinib, a well-known epidermal growth factor receptor (EGFR) inhibitor. Beyond this specific application, it functions as a versatile scaffold for developing novel quinazoline-based compounds. Medicinal chemists value this material for its reactivity profile, which facilitates efficient coupling reactions during multi-step synthesis routes. Our supply supports both large-scale commercial production and small-batch laboratory experimentation, ensuring flexibility for diverse project requirements.

Quality Assurance and Safety

We maintain a robust quality control system that includes HPLC, NMR, and mass spectrometry analysis for every batch produced. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) to verify compliance with specified parameters. Regarding safety, handlers should utilize appropriate personal protective equipment, including gloves and eye protection, during transfer operations. The material should be processed in well-ventilated areas to minimize exposure to dust. Our facility adheres to strict environmental and safety regulations to guarantee responsible manufacturing practices.

Packaging and Storage

To preserve integrity during transit, the product is packaged in 25kg cardboard drums or customized containers based on client specifications. Storage requirements include maintaining a cool, dry environment in well-closed containers. It is essential to protect the material from moisture and strong light or heat sources, which could degrade chemical stability over time. Our logistics team ensures secure global shipping with detailed documentation to streamline customs clearance and delivery processes.