Industrial Purity 1-Fluoro-3-Bromopropane COA Specs and Bulk Supply Analysis
- [Reaction Engineering]: Optimized halogen exchange protocols ensure minimal di-halogenated impurities and consistent yield profiles for scale-up.
- [Procurement Logic]: Factory-direct channels eliminate intermediary markups, stabilizing bulk price structures for tonnage quantities.
- [Audit Readiness]: Comprehensive documentation packages include batch-specific COA, SDS, and regulatory compliance statements for global shipping.
In the landscape of fine chemical intermediates, securing a reliable source for halogenated building blocks is critical for maintaining production continuity. 1-Fluoro-3-bromopropane (CAS 352-91-0) serves as a vital precursor in the synthesis of pharmaceuticals, agrochemicals, and specialty polymers. As a premier global manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. delivers process-scale purity that meets the rigorous demands of industrial applications. This technical overview details the critical quality attributes, synthesis considerations, and supply chain advantages necessary for strategic procurement.
Technical Specifications and Quality Parameters
For procurement teams and quality assurance managers, verifying the physical and chemical properties against the Certificate of Analysis (COA) is the first step in vendor qualification. The following table outlines the standard industrial specifications expected for commercial grade material. Deviations in boiling point or density often indicate the presence of isomeric impurities or residual solvents.
| Parameter | Specification Standard | Typical Industrial Value |
|---|---|---|
| CAS Number | 352-91-0 | 352-91-0 |
| Molecular Formula | C3H6BrF | C3H6BrF |
| Molecular Weight | 140.98 g/mol | 140.98 g/mol |
| Purity (GC Area %) | ≥ 99.0% | 99.2% - 99.5% |
| Boiling Point | 101.2 ± 8.0 °C (760 mmHg) | 99 - 101 °C |
| Density | 1.5 ± 0.1 g/cm³ | 1.58 g/cm³ @ 25°C |
| Refractive Index | 1.408 ± 0.005 | 1.408 |
| Water Content (Karl Fischer) | ≤ 0.1% | < 0.05% |
Synthesis Routes and Impurity Profiles for R&D
For process chemists evaluating this alkyl halide for downstream reactions, understanding the manufacturing process is essential for predicting reactivity and impurity carryover. The production of 1-Bromo-3-fluoropropane typically involves halogen exchange reactions or direct fluorination of brominated precursors. A robust synthesis route minimizes the formation of poly-halogenated byproducts and ensures the terminal functional groups remain intact for nucleophilic substitution.
Common impurities monitored during gas chromatography (GC) analysis include residual starting materials and isomeric bromofluoropropanes. High-quality factory supply ensures that these impurities are kept below detection limits, preventing catalyst poisoning in subsequent coupling reactions. When scaling from gram to kilogram levels, maintaining batch-to-batch consistency in the FBP (fluorobromopropane) profile is paramount for reproducible reaction yields.
Procurement Stability and Bulk Pricing Dynamics
Supply chain volatility often impacts the availability of specialized fluorinated intermediates. Strategic buyers prioritize partners who offer transparent bulk price structures and guaranteed production capacity. Unlike trading companies, a dedicated manufacturer can control the manufacturing process from raw material sourcing to final distillation, ensuring stability even during market fluctuations.
When sourcing high-purity 1-Fluoro-3-bromopropane, buyers should verify the supplier's ability to provide tonnage quantities without compromising on industrial purity. NINGBO INNO PHARMCHEM CO.,LTD. maintains extensive inventory levels and flexible packaging options to support both pilot plant trials and full-scale commercial production. This direct engagement reduces lead times and mitigates the risk of supply interruptions common in fragmented distribution networks.
Regulatory Compliance and Safety Handling
Executive decision-makers must account for regulatory frameworks such as REACH and TSCA when importing chemical building blocks. This substance is classified as a flammable liquid (UN 1993, Packing Group III) and requires adherence to strict storage and transport guidelines. Proper documentation, including a valid COA and Safety Data Sheet (SDS), is mandatory for customs clearance and workplace safety compliance.
Handling protocols dictate the use of explosion-proof equipment and adequate ventilation due to the vapor pressure and flammability characteristics. Ensuring that your supply partner complies with international shipping regulations prevents logistical delays and liability issues. Our team ensures all shipments are accompanied by comprehensive regulatory dossiers suitable for audit.
Secure Your Supply Chain Today
Reliable access to high-performance intermediates is the backbone of efficient chemical manufacturing. By partnering with a verified producer, you secure not only the material but also the technical support required for successful integration into your process.
To proceed with vendor qualification or request a sample for testing, please contact our technical sales team for a batch-specific COA, SDS, or bulk pricing quote.