Intermediates

1-Fluoro-3-bromopropane

  • CAS No.352-91-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 1-Fluoro-3-bromopropane (CAS 352-91-0) designed for advanced organic synthesis. Reliable supply for pharmaceutical and agrochemical manufacturing processes.

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Product Technical Details

Product Overview

1-Fluoro-3-bromopropane is a specialized fluorinated alkyl halide serving as a critical building block in modern organic chemistry. As a versatile intermediate, this compound combines the stability of the carbon-fluorine bond with the reactivity of the bromine substituent, enabling diverse synthetic transformations. Our facility produces this chemical under strict quality control standards to ensure consistency for downstream applications in pharmaceuticals, agrochemicals, and advanced material science.

The introduction of fluorine atoms into organic molecules often enhances metabolic stability and bioavailability, making fluoro-intermediates highly valuable in drug discovery. This specific bromo-fluoro alkane allows chemists to introduce a three-carbon chain with terminal functionality, facilitating nucleophilic substitution reactions essential for constructing complex molecular architectures.

Key Specifications

We maintain rigorous testing protocols to guarantee that every batch meets international standards for purity and composition. The following table outlines the typical physical and chemical properties of our commercial grade product.

ParameterSpecification
Chemical Name1-Fluoro-3-bromopropane
CAS Number352-91-0
Molecular FormulaC3H6BrF
Molecular Weight140.98 g/mol
AppearanceColorless transparent liquid
Purity (Assay)≥99.0%
Moisture Content≤0.05%
Density1.458 g/cm3
Refractive Index1.4295

Industrial Applications

This compound is primarily utilized as a synthesis intermediate where selective functionalization is required. The bromine atom acts as an excellent leaving group, allowing for coupling reactions with various nucleophiles. Common uses include:

  • Pharmaceutical Intermediate Synthesis: Used in the construction of fluorinated side chains for active pharmaceutical ingredients (APIs).
  • Agrochemical Development: Serves as a precursor for novel pesticides and herbicides requiring fluorinated motifs.
  • Material Science: Employed in the modification of polymers to enhance surface properties and chemical resistance.
  • Research and Development: A standard reagent for organic chemistry laboratories focusing on halogen exchange reactions.

Quality Assurance and Safety

Quality is paramount in our manufacturing process. Each production lot undergoes comprehensive analysis using Gas Chromatography (GC) and Karl Fischer titration to verify purity and moisture levels. We provide a Certificate of Analysis (COA) with every shipment to ensure full traceability and compliance with your internal quality systems.

Regarding safety, this chemical should be handled in a well-ventilated environment using appropriate personal protective equipment. It is classified as a flammable liquid and should be stored away from heat sources and oxidizing agents. Our packaging ensures secure transport, minimizing the risk of leakage or contamination during global shipping.

Packaging and Logistics

We offer flexible packaging solutions to meet the diverse needs of our B2B clients. Standard packaging includes 200 kg drums, which are optimized for industrial use and storage efficiency. Custom packaging configurations are available upon request to align with specific supply chain requirements. Our logistics team coordinates global shipping, ensuring timely delivery while adhering to all international hazardous material transport regulations.